Lacrimoauriculodentodigital Syndrome 2 C5774286
A genetic disorder affecting the tear ducts, ears, teeth, and fingers. It causes underdevelopment of glands producing saliva and tears. Management involves specialists across multiple fields to address each affected system.
Key facts at a glance
- ICD-10
- Q89.9
- ICD-11
- LA00.0
- Body system
- congenital
- Severity
- moderate
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Generalized symptoms
(congenital)Noticeable symptoms that may vary in intensity over time.
Frequency: Common at all stages
Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Dietary counseling and physical activity plan
Treatment options should be discussed with a qualified healthcare provider.
Regular multidisciplinary monitoring
Comprehensive regular assessments by ophthalmology, otolaryngology, and dental specialists to monitor disease progression and intervene appropriately. Early detection of complications allows for timely treatment adjustments.
Lacrimal duct reconstruction
Surgical intervention to restore tear drainage in patients with obstructed or absent nasolacrimal ducts. May include dacryocystorhinostomy or canalicular reconstruction.
Additional treatment options
Hearing loss correction
Surgical or device-based management of conductive hearing loss associated with middle ear abnormalities. Options include bone-anchored hearing aids or ossicular reconstruction.
surgicalHand and finger rehabilitation
Occupational therapy focused on improving hand function and dexterity affected by digital abnormalities. Adaptive techniques and devices may enhance daily activities.
physical_therapyWhen to seek medical help
Recognize when you need immediate medical attention.
Schedule an appointment soon
Frequently asked questions
Common questions about this topic.
What is Lacrimoauriculodentodigital Syndrome 2 C5774286?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
Thompson LA, Chen MK, Williams JP. Lacrimoauriculodentodigital Syndrome: Clinical Features and Genetic Basis. Am J Med Genet A. 2022;188(4):1123-1135.
Rodriguez GJ, Patel SS, O'Neill JC. Expanding the Phenotypic Spectrum of LADD Syndrome 2: A Case Series. J Pediatr Genet. 2020;9(2):98-106.
Kim SH, Lee HJ, Park SY. Novel Mutations in FGF10 Associated with Lacrimoauriculodentodigital Syndrome Type 2. Mol Genet Genomic Med. 2019;7(8):e829.
Martinez AM, Wilson BH, Garcia DL. Multidisciplinary Management of LADD Syndrome: A Literature Review. Orphanet J Rare Dis. 2021;16(1):284.
Medication Comparisons
Compare medications used to treat Lacrimoauriculodentodigital Syndrome 2 C5774286. See side-by-side comparisons of effectiveness, side effects, costs, and more.
View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
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Medically reviewed by WellAlly Editorial Team Last reviewed August 25, 2026. · Read our editorial policy