Machado Joseph Disease Type 2 C0751669
A progressive neurological condition affecting coordination, balance, and muscle control. Management focuses on supportive care and rehabilitation.
Key facts at a glance
- ICD-10
- G43.909
- ICD-11
- 8A00.0
- Body system
- neurologic
- Severity
- severe
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Ataxia
(neurologic)Generalized symptoms
(neurologic)Significant symptoms that substantially affect daily functioning.
Frequency: Common at all stages
Peripheral neuropathy
(neurologic)Dysarthria
(neurologic)Urinary dysfunction
(neurologic)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Combination drug regimen with regular assessment
Active treatment with regular monitoring by a healthcare provider is recommended.
Comprehensive Physical Therapy Program
Individualized exercise program focusing on balance training, gait retraining, and coordination exercises to maintain mobility and reduce fall risk.
Symptomatic Spasticity Management
Muscle relaxants such as baclofen or tizanidine to manage spasticity and improve comfort. Dosing varies by individual tolerance and response.
Additional treatment options
Acupuncture for Pain Management
Traditional acupuncture may provide complementary relief for neuropathic pain and muscle stiffness associated with the condition.
complementaryNeuropsychological Support
Counseling and cognitive behavioral therapy to address depression, anxiety, and adjustment to progressive symptoms.
psychologicalMultidisciplinary Surveillance
Regular monitoring by neurology, physiatry, and rehabilitation specialists to track disease progression and adjust interventions.
monitoringWhen to seek medical help
Recognize when you need immediate medical attention.
See a doctor within 24 hours
Moderate to severe symptoms that may indicate worsening of this condition. Prompt medical evaluation is recommended.
Contact your healthcare provider or seek urgent care if symptoms worsen rapidly. Go to the emergency department for life-threatening symptoms.
Frequently asked questions
Common questions about this topic.
What is Machado Joseph Disease Type 2 C0751669?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalMedication Comparisons
Compare medications used to treat Machado Joseph Disease Type 2 C0751669. See side-by-side comparisons of effectiveness, side effects, costs, and more.
View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 25, 2026. · Read our editorial policy