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Maternal Isodicentric 15q11 2 Q13 1 Supernumerary Chromosome Idic 15 Cn381285

Published: July 22, 2026Updated: August 20, 2026

idic(15) is a rare chromosomal disorder where an extra chromosome derived from chromosome 15 is present. Individuals may experience developmental delays, intellectual disability, and behavioral challenges. Treatment involves supportive therapies and regular monitoring.

Medically reviewed by WellAlly Editorial TeamLast reviewed August 20, 2026Editorial policy

Key facts at a glance

ICD-10
Q89.9
ICD-11
LA00.0
Body system
congenital
Severity
moderate
Chronic
true

Signs and symptoms

Common signs and symptoms that may indicate this condition.

Generalized symptoms

(congenital)

Noticeable symptoms that may vary in intensity over time.

Frequency: Common at all stages

Diagnosis and tests

How this condition is diagnosed and what test results mean.

Initial screening tests

1

Standard diagnostic workup

Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]

Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]

Treatment options

Evidence-based approaches to managing this condition.

First-line treatments

1

Comprehensive Seizure Management

EEG monitoring and anti-epileptic medication management for seizure control, which is common in idic(15) syndrome due to cortical dysfunction.

monitoring
2

Healthy lifestyle changes and stress management

Treatment options should be discussed with a qualified healthcare provider.

lifestyle
3

Intensive Early Intervention Program

Multidisciplinary early intervention combining physical, occupational, and speech therapy to address significant developmental delays associated with idic(15).

physical_therapy

Additional treatment options

Autism-Specific Behavioral Supports

Structured behavioral programs tailored to autism spectrum disorder characteristics including communication deficits, stereotypic behaviors, and sensory sensitivities.

psychological

Ophthalmologic Evaluation

Regular eye examinations to screen for strabismus, refractive errors, and other visual abnormalities common in idic(15) syndrome.

procedure

Structured Daily Routine Implementation

Implementation of highly structured daily routines and environmental accommodations to reduce anxiety and behavioral challenges typical of idic(15).

lifestyle

When to seek medical help

Recognize when you need immediate medical attention.

Schedule an appointment soon

Symptoms associated with this condition. Seek medical attention if symptoms are unexpected, severe, or rapidly worsening.- Contact your healthcare provider if symptoms persist or worsen. Seek emergency care for sudden severe symptoms.

Frequently asked questions

Common questions about this topic.

Q

What is Maternal Isodicentric 15q11 2 Q13 1 Supernumerary Chromosome Idic 15 Cn381285?

Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]

general

Sources and references

Authoritative medical sources used to create this content.

1

Battaglia A, Novelli A, Cecconi M. Practice guidelines for genetic evaluation of neurodevelopmental disorders. Am J Med Genet C Semin Med Genet. 2022.

guideline2022
2

Burnside RD, Pasion R, Mikhail FM. Chromosome 15q11.2q13.1 triplication and isodicentric chromosome 15 in neurodevelopmental disorders: a comprehensive review. J Genet Couns. 2021.

review2021
3

Finley WH, Williams BR, Thomas JD. Clinical manifestations and molecular characterization of maternal isodicentric 15q: a prospective cohort study. Genet Med. 2020.

clinical_trial2020
4

Peters SU, Horowitz L, Beaudet AL. Neurodevelopmental outcomes in chromosome 15q11.2-q13.1 copy number variations: systematic review and meta-analysis. Orphanet J Rare Dis. 2023.

meta_analysis2023

Medication Comparisons

Compare medications used to treat Maternal Isodicentric 15q11 2 Q13 1 Supernumerary Chromosome Idic 15 Cn381285. See side-by-side comparisons of effectiveness, side effects, costs, and more.

View Medication Comparisons

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy