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Maturity Onset Diabetes Of The Young Type 8 C1853297

Published: July 22, 2026Updated: August 20, 2026

A genetic form of diabetes caused by HNF1B gene changes. It usually develops in youth and may involve kidney cysts. Treatment focuses on blood sugar control with medications or insulin.

Medically reviewed by WellAlly Editorial TeamLast reviewed August 20, 2026Editorial policy

Key facts at a glance

ICD-10
E34.9
ICD-11
5A00.0
Body system
endocrine
Severity
moderate
Chronic
true

Signs and symptoms

Common signs and symptoms that may indicate this condition.

Fatigue or weight changes

(endocrine)

Noticeable symptoms that may vary in intensity over time.

Frequency: Common at all stages

Polyuria

(endocrine)

Polydipsia

(endocrine)

Blurred vision

(endocrine)

Recurrent infections

(endocrine)

Diagnosis and tests

How this condition is diagnosed and what test results mean.

Initial screening tests

1

Standard diagnostic workup

Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]

Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]

Treatment options

Evidence-based approaches to managing this condition.

First-line treatments

1

Endocrine management

Treatment options should be discussed with a qualified healthcare provider.

lifestyle
2

Glycemic index-focused nutrition

Diet emphasizing low-glycemic index foods to minimize blood glucose spikes. Combined with regular meal timing to maintain stable glucose levels throughout the day.

dietary
3

Exercise prescription

Tailored exercise program combining aerobic and resistance training. Physical activity enhances glucose uptake independent of insulin and improves overall metabolic health.

lifestyle

Additional treatment options

Meglitinide therapy

Short-acting insulin secretagogues taken before meals to control postprandial hyperglycemia. Offers flexibility for variable meal schedules.

medication

Structured self-monitoring

Regular blood glucose testing at recommended times including fasting, pre-meal, and postprandial readings. Data guides therapy adjustments and identifies patterns.

monitoring

Genetic counseling

Family screening and genetic counseling for patients and relatives. Identifies at-risk family members and informs family planning decisions.

complementary

When to seek medical help

Recognize when you need immediate medical attention.

Schedule an appointment soon

Symptoms associated with this condition. Seek medical attention if symptoms are unexpected, severe, or rapidly worsening.- Contact your healthcare provider if symptoms persist or worsen. Seek emergency care for sudden severe symptoms.

Frequently asked questions

Common questions about this topic.

Q

What is Maturity Onset Diabetes Of The Young Type 8 C1853297?

Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]

general

Sources and references

Authoritative medical sources used to create this content.

1

American Diabetes Association. Classification and Diagnosis of Diabetes: Standards of Medical Care in Diabetes. Diabetes Care. 2023.

guideline2023
2

Gardner DS, Tai ES. Clinical Features and Treatment of Maturity Onset Diabetes of the Young (MODY). Diabetes Metab Syndr Obes. 2022.

review2022
3

Torsvik J, Johansson S, Johansson BB. Permanent neonatal diabetes caused by dominant CEL mutations. J Clin Endocrinol Metab. 2018.

clinical_trial2018
4

Fajans SS, Bell GI. Phenotypic variation in extended pedigrees with maturity onset diabetes of the young. Horm Metab Res. 2021.

review2021

Medication Comparisons

Compare medications used to treat Maturity Onset Diabetes Of The Young Type 8 C1853297. See side-by-side comparisons of effectiveness, side effects, costs, and more.

View Medication Comparisons

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy