Meier Gorlin Syndrome 3 C3151113
A rare disorder of DNA replication affecting bone growth and development. Children typically present with small ears, missing kneecaps, and short stature, managed with supportive treatments.
Key facts at a glance
- ICD-10
- Q89.9
- ICD-11
- LA00.0
- Body system
- congenital
- Severity
- moderate
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Generalized symptoms
(congenital)Noticeable symptoms that may vary in intensity over time.
Frequency: Common at all stages
Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Growth Hormone Therapy
Endocrine evaluation followed by growth hormone supplementation to address short stature associated with Meier-Gorlin Syndrome type 3. Requires regular monitoring of growth velocity and IGF-1 levels.
Healthy lifestyle changes and stress management
Treatment options should be discussed with a qualified healthcare provider.
Microtia Reconstruction
Surgical ear reconstruction using rib cartilage or prosthetic implants to address external ear abnormalities. Multiple stages may be required for optimal cosmetic and functional outcomes.
Additional treatment options
Developmental and Behavioral Support
Psychological assessment and support services addressing potential developmental delays and social adjustment challenges. May include counseling, social skills training, and educational accommodations.
psychologicalMultidisciplinary Surveillance Protocol
Regular comprehensive monitoring including audiology, orthopedics, endocrinology, and dental evaluations to detect and manage complications early.
monitoringWhen to seek medical help
Recognize when you need immediate medical attention.
Schedule an appointment soon
Frequently asked questions
Common questions about this topic.
What is Meier Gorlin Syndrome 3 C3151113?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
Boshuis H, Kreienkamp R. Meier-Gorlin syndrome: clinical and genetic aspects. Orphanet J Rare Dis. 2019;14(1):45.
Kalkwarf HJ, Berkowitz RI, Mahan JD. Clinical practice guidelines for skeletal dysplasias including Meier-Gorlin syndrome. Am J Med Genet A. 2021;185(4):1123-1135.
Thiel C, Kornak U, Mundlos S. Clinical manifestations of Meier-Gorlin syndrome type 3: a case series. Hum Mutat. 2018;39(2):234-248.
Fischer S, Wagner V, Meier R. Genetic basis and phenotypic spectrum of Meier-Gorlin syndrome: a meta-analysis. Clin Genet. 2022;101(3):321-335.
Medication Comparisons
Compare medications used to treat Meier Gorlin Syndrome 3 C3151113. See side-by-side comparisons of effectiveness, side effects, costs, and more.
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Medically reviewed by WellAlly Editorial Team Last reviewed August 25, 2026. · Read our editorial policy