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Migraine Familial Hemiplegic 2 C1865322

Published: July 22, 2026Updated: August 25, 2026

An inherited migraine disorder causing headaches with temporary weakness on one side of the body. It runs in families and requires careful trigger management. Treatment includes standard migraine medications.

Medically reviewed by WellAlly Editorial TeamLast reviewed August 25, 2026Editorial policy

Key facts at a glance

ICD-10
G40.909
ICD-11
8A00.0
Body system
neurologic
Severity
severe
Chronic
true

Signs and symptoms

Common signs and symptoms that may indicate this condition.

Warning signs - seek immediate care

!

Hemiplegic migraine attacks

Generalized symptoms

(neurologic)

Significant symptoms that substantially affect daily functioning.

Frequency: Common at all stages

Severe throbbing headache

(neurologic)

Sensory aphasia

(neurologic)

Ataxia between attacks

(neurologic)

Diagnosis and tests

How this condition is diagnosed and what test results mean.

Initial screening tests

1

Standard diagnostic workup

Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]

Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]

Treatment options

Evidence-based approaches to managing this condition.

First-line treatments

1

Acetazolamide

Carbonic anhydrase inhibitor commonly used as first-line prophylactic treatment for familial hemiplegic migraine, helping to reduce attack frequency and severity by stabilizing neuronal excitability.

medication
2

Drug therapy with clinical monitoring

Active treatment with regular monitoring by a healthcare provider is recommended.

medication
3

Calcium Channel Blockers

Verapamil or diltiazem may be prescribed for migraine prophylaxis when acetazolamide is ineffective or contraindicated, working through vasodilatory and neurostabilizing mechanisms.

medication

Additional treatment options

Migraine Trigger Avoidance

Systematic identification and avoidance of personal migraine triggers including stress, specific foods, sleep disturbances, and environmental factors to reduce attack frequency.

lifestyle

Post-Attack Rehabilitation

Targeted physical therapy focusing on motor recovery, strength training, and balance exercises following hemiplegic episodes to address residual weakness.

physical_therapy

Neurological Monitoring

Regular neurological assessments and imaging studies to monitor disease progression, assess treatment efficacy, and rule out secondary causes of symptoms.

monitoring

When to seek medical help

Recognize when you need immediate medical attention.

See a doctor within 24 hours

Moderate to severe symptoms that may indicate worsening of this condition. Prompt medical evaluation is recommended.

Contact your healthcare provider or seek urgent care if symptoms worsen rapidly. Go to the emergency department for life-threatening symptoms.

Frequently asked questions

Common questions about this topic.

Q

What is Migraine Familial Hemiplegic 2 C1865322?

Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]

general

Medication Comparisons

Compare medications used to treat Migraine Familial Hemiplegic 2 C1865322. See side-by-side comparisons of effectiveness, side effects, costs, and more.

View Medication Comparisons

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 25, 2026. · Read our editorial policy