Mismatch Repair Cancer Syndrome 3 C5436807
A genetic condition that increases risk of developing cancer due to impaired DNA repair. It affects children and requires regular cancer screenings. Early detection and monitoring are essential.
Key facts at a glance
- ICD-10
- C80.1
- ICD-11
- 2A00.0
- Body system
- oncologic
- Severity
- severe
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Warning signs - seek immediate care
Rectal bleeding
Change in bowel habits
(oncologic)Generalized symptoms
(oncologic)Significant symptoms that substantially affect daily functioning.
Frequency: Common at all stages
Abdominal pain
(oncologic)Weight loss
(oncologic)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Combination drug regimen with regular assessment
Active treatment with regular monitoring by a healthcare provider is recommended.
Enhanced Cancer Surveillance Program
Comprehensive surveillance protocol including regular colonoscopic examinations, upper GI endoscopy, and imaging studies to detect malignancies at early, treatable stages.
Prophylactic Surgical Interventions
Consideration of prophylactic colectomy or other organ removal in consultation with genetics and surgical teams when cancer risk becomes prohibitive or early neoplasia is detected.
Additional treatment options
Immunomodulatory Therapy
Certain immunomodulatory approaches may be considered as adjunctive therapy to support immune surveillance and potentially reduce tumor development in mismatch repair deficiency.
medicationNutritional Support
Comprehensive nutritional support and supplementation to maintain optimal growth, immune function, and overall health status in children with chronic illness.
complementaryFamily Counseling and Support Services
Psychological support services for the entire family addressing the challenges of managing a hereditary cancer predisposition syndrome including genetic counseling for family planning.
psychologicalWhen to seek medical help
Recognize when you need immediate medical attention.
See a doctor within 24 hours
Moderate to severe symptoms that may indicate worsening of this condition. Prompt medical evaluation is recommended.
Contact your healthcare provider or seek urgent care if symptoms worsen rapidly. Go to the emergency department for life-threatening symptoms.
Frequently asked questions
Common questions about this topic.
What is Mismatch Repair Cancer Syndrome 3 C5436807?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalMedication Comparisons
Compare medications used to treat Mismatch Repair Cancer Syndrome 3 C5436807. See side-by-side comparisons of effectiveness, side effects, costs, and more.
View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy