Moyamoya Disease 2 C1846689
A genetic form of Moyamoya disease where brain blood vessels progressively narrow, affecting blood supply to the brain. It can develop in childhood or adulthood and may lead to stroke. Surgical procedures can help improve brain circulation.
Key facts at a glance
- ICD-10
- G40.909
- ICD-11
- 8A00.0
- Body system
- neurologic
- Severity
- severe
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Warning signs - seek immediate care
Transient ischemic attacks (TIA)
Ischemic stroke
Seizures
Generalized symptoms
(neurologic)Significant symptoms that substantially affect daily functioning.
Frequency: Common at all stages
Headache
(neurologic)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Cerebral revascularization procedures
Surgical revascularization through direct bypass, indirect bypass, or combined approaches to restore perfusion to affected brain regions and prevent ischemic complications.
Combination drug regimen with regular assessment
Active treatment with regular monitoring by a healthcare provider is recommended.
Additional treatment options
Advanced cerebrovascular monitoring
Quantitative imaging including perfusion studies and vasoreactivity testing to assess hemodynamic reserve and determine optimal timing for surgical intervention.
monitoringVasodilator and antiplatelet therapy
Pharmacological management using vasodilators to improve cerebral blood flow and antiplatelet agents to reduce thrombotic risk in Moyamoya disease.
medicationNeurocognitive support
Neuropsychological evaluation and cognitive rehabilitation for patients experiencing cognitive decline, attention deficits, or memory issues related to cerebrovascular compromise.
psychologicalRisk factor management and activity modification
Comprehensive lifestyle modifications including avoidance of dehydrating conditions, extreme temperatures, and high-risk activities that may precipitate ischemic events.
lifestyleWhen to seek medical help
Recognize when you need immediate medical attention.
See a doctor within 24 hours
Moderate to severe symptoms that may indicate worsening of this condition. Prompt medical evaluation is recommended.
Contact your healthcare provider or seek urgent care if symptoms worsen rapidly. Go to the emergency department for life-threatening symptoms.
Frequently asked questions
Common questions about this topic.
What is Moyamoya Disease 2 C1846689?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
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Compare medications used to treat Moyamoya Disease 2 C1846689. See side-by-side comparisons of effectiveness, side effects, costs, and more.
View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 25, 2026. · Read our editorial policy