Neuroblastoma Susceptibility To 1 C2749485
A genetic condition increasing risk of neuroblastoma, a cancer of nerve tissue. Children with this susceptibility require monitoring for early detection.
Key facts at a glance
- ICD-10
- C80.1
- ICD-11
- 2A00.0
- Body system
- oncologic
- Severity
- severe
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Generalized symptoms
(oncologic)Significant symptoms that substantially affect daily functioning.
Frequency: Common at all stages
Palpable abdominal mass
(abdominal)Bone pain
(musculoskeletal)Constitutional symptoms (fever, weight loss)
(systemic)Hypertension
(cardiovascular)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Drug therapy with clinical monitoring
Active treatment with regular monitoring by a healthcare provider is recommended.
Tumor surveillance program
Regular screening with ultrasound, urine catecholamine testing, and periodic imaging allows for early detection of neuroblastoma. Surveillance protocols are typically followed until age 8-10 years when spontaneous regression is more likely.
Genetic counseling and family support
Families benefit from genetic counseling to understand inheritance patterns, recurrence risks, and available testing options. Psychological support helps manage anxiety associated with cancer predisposition syndromes.
Additional treatment options
Chemotherapy protocols
High-risk neuroblastoma typically requires intensive multi-agent chemotherapy as part of multimodal treatment. Regimens may include cisplatin, etoposide, cyclophosphamide, and doxorubicin.
medicationPrimary tumor resection
Surgical removal of the primary tumor when feasible, often combined with chemotherapy and radiation. Complete resection improves survival in localized disease.
surgicalPsychosocial support intervention
Ongoing psychological support addresses anxiety, depression, and quality of life concerns common in cancer predisposition syndromes. Includes individual and family counseling.
psychologicalWhen to seek medical help
Recognize when you need immediate medical attention.
See a doctor within 24 hours
Moderate to severe symptoms that may indicate worsening of this condition. Prompt medical evaluation is recommended.
Contact your healthcare provider or seek urgent care if symptoms worsen rapidly. Go to the emergency department for life-threatening symptoms.
Frequently asked questions
Common questions about this topic.
What is Neuroblastoma Susceptibility To 1 C2749485?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalMedication Comparisons
Compare medications used to treat Neuroblastoma Susceptibility To 1 C2749485. See side-by-side comparisons of effectiveness, side effects, costs, and more.
View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy