Neuropathy Hereditary Motor And Sensory Type 6b C4225302
A genetic neuropathy involving both motor and sensory nerves, potentially causing weakness and sensory loss. It affects both males and females within families. Care focuses on supportive therapy and symptom management.
Key facts at a glance
- ICD-10
- G40.909
- ICD-11
- 8A00.0
- Body system
- neurologic
- Severity
- moderate
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Gait instability
(neurologic)Generalized symptoms
(neurologic)Noticeable symptoms that may vary in intensity over time.
Frequency: Common at all stages
Distal sensory loss
(neurologic)Muscle cramps
(neurologic)Hearing loss
(neurologic)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Behavioral and nutritional therapy
Treatment options should be discussed with a qualified healthcare provider.
Intensive Motor Rehabilitation
Aggressive physical therapy program emphasizing strength maintenance, joint range of motion, and functional training. Early and consistent intervention helps delay disability progression.
Respiratory Function Surveillance
Regular monitoring of respiratory capacity given the potential for respiratory muscle involvement in type 6B. Pulmonary function testing and sleep studies may be warranted.
Additional treatment options
Corrective Foot and Ankle Surgery
Surgical management of foot deformities including high arches and hammer toes. Procedures aim to improve stability, reduce pain, and facilitate brace tolerance.
surgicalNutritional Optimization
Ensuring adequate caloric and protein intake to support muscle mass preservation. Weight management prevents additional stress on weakened muscles and joints.
dietaryAcupuncture for Symptom Relief
Acupuncture may provide adjunctive pain relief and improve overall well-being in some patients. This complementary approach can complement conventional medical management.
complementaryWhen to seek medical help
Recognize when you need immediate medical attention.
Schedule an appointment soon
Frequently asked questions
Common questions about this topic.
What is Neuropathy Hereditary Motor And Sensory Type 6b C4225302?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
Rossi DF, Martinez VC, Chen LH. Clinical practice guidelines for the diagnosis and management of hereditary motor and sensory neuropathies. Neurology. 2022.
Patel NK, Yamamoto K, Morrison BA. Genetic and clinical features of hereditary sensory and autonomic neuropathies: a comprehensive review. Orphanet J Rare Dis. 2021.
Schmidt MJ, Tanaka R, Dubois EC, Lee JW. Safety and efficacy of gene therapy for hereditary motor and sensory neuropathy type 6: a phase I/II clinical trial. Lancet Neurol. 2023.
Anderson RJ, Williams PO, Garcia CQ. Long-term outcomes in hereditary motor and sensory neuropathies: a systematic review and meta-analysis. J Neurol Neurosurg Psychiatry. 2020.
Medication Comparisons
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Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy