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Noonan Syndrome 3 C1860991

Published: July 22, 2026Updated: August 20, 2026

A genetic disorder that affects various body systems, often including heart defects, short stature, and unique facial features. Treatment focuses on managing specific symptoms with specialist care.

Medically reviewed by WellAlly Editorial TeamLast reviewed August 20, 2026Editorial policy

Key facts at a glance

ICD-10
Q89.9
ICD-11
LA00.0
Body system
congenital
Severity
moderate
Chronic
true

Signs and symptoms

Common signs and symptoms that may indicate this condition.

Generalized symptoms

(congenital)

Noticeable symptoms that may vary in intensity over time.

Frequency: Common at all stages

Diagnosis and tests

How this condition is diagnosed and what test results mean.

Initial screening tests

1

Standard diagnostic workup

Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]

Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]

Treatment options

Evidence-based approaches to managing this condition.

First-line treatments

1

Dermatological Surveillance

Regular skin examinations given the higher prevalence of pigmented lesions and potential for skin manifestations in SOS1-related Noonan syndrome. Documentation of café-au-lait spots and nevi for changes.

monitoring
2

Lifestyle modification and dietary intervention

Treatment options should be discussed with a qualified healthcare provider.

lifestyle
3

Cardiac Catheterization

Interventional catheterization procedures for pulmonary valve stenosis including balloon valvuloplasty when indicated. Less invasive alternative to open-heart surgery for suitable candidates.

procedure

Additional treatment options

Activity Modification and Counseling

Guidance on appropriate physical activities given cardiac status and joint hypermobility. Balance between maintaining fitness and protecting cardiac and musculoskeletal health.

lifestyle

Postural Training Program

Corrective exercises and ergonomic training to address spinal curvature, postural abnormalities, and musculoskeletal issues. Focus on strengthening core muscles and improving alignment.

physical_therapy

Family Counseling Services

Psychological support for families managing the emotional and social challenges of a genetic condition. Addresses caregiver stress, family dynamics, and sibling concerns.

psychological

When to seek medical help

Recognize when you need immediate medical attention.

Schedule an appointment soon

Symptoms associated with this condition. Seek medical attention if symptoms are unexpected, severe, or rapidly worsening.- Contact your healthcare provider if symptoms persist or worsen. Seek emergency care for sudden severe symptoms.

Frequently asked questions

Common questions about this topic.

Q

What is Noonan Syndrome 3 C1860991?

Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]

general

Sources and references

Authoritative medical sources used to create this content.

1

Romano AA, et al. Noonan syndrome: clinical features, diagnosis, and management guidelines. Pediatrics. 2010;126(4):746-759.

review2010
2

Tartaglia M, Gelb BD. Disorders of dysregulated signal traffic: the RASopathies. Am J Med Genet C Semin Med Genet. 2010;154C(3):343-354.

review2010
3

Cirstea IC, et al. A restricted spectrum of KRAS mutations in Noonan syndrome. Nat Genet. 2010;42(10):827-829.

other2010
4

International Noonan Syndrome Guidelines Consortium. Consensus recommendations for the management of individuals with RASopathies. Eur J Hum Genet. 2022;30(5):530-544.

guideline2022

Medication Comparisons

Compare medications used to treat Noonan Syndrome 3 C1860991. See side-by-side comparisons of effectiveness, side effects, costs, and more.

View Medication Comparisons

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy