O Donnell Luria Rodan Syndrome C5193138
A rare genetic neurological disorder affecting development and brain function. It typically causes intellectual disability and other developmental challenges. Management focuses on supportive therapies and addressing individual symptoms.
Key facts at a glance
- ICD-10
- G40.909
- ICD-11
- 8A00.0
- Body system
- neurologic
- Severity
- moderate
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Generalized symptoms
(neurologic)Noticeable symptoms that may vary in intensity over time.
Frequency: Common at all stages
Seizures
(neurologic)Developmental delay
(neurologic)Hypotonia
(neurologic)Autistic features
(neurologic)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Lifestyle modification and dietary intervention
Treatment options should be discussed with a qualified healthcare provider.
Symptomatic Pharmacological Management
Targeted medication therapy to address specific neurological manifestations such as seizures, anxiety, or attention deficits associated with the syndrome. Medications are selected based on presenting symptoms and adjusted over time.
Developmental Physical Therapy
Structured physical therapy program focusing on motor skill development, coordination, and functional mobility. Sessions typically include gait training, balance exercises, and strength building activities.
Additional treatment options
Behavioral and Cognitive Interventions
Individualized behavioral therapy and cognitive support to address developmental delays, social difficulties, and emotional regulation challenges commonly seen in this condition.
psychologicalMultidisciplinary Developmental Monitoring
Regular comprehensive assessments by a team of specialists to track developmental progress, neurological function, and response to interventions over time.
monitoringStructured Daily Routine and Environmental Support
Implementation of consistent daily schedules, environmental modifications, and sensory accommodations to support optimal functioning and reduce anxiety in daily life.
lifestyleWhen to seek medical help
Recognize when you need immediate medical attention.
Schedule an appointment soon
Frequently asked questions
Common questions about this topic.
What is O Donnell Luria Rodan Syndrome C5193138?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
Thompson DM, Anderson BC, Chen X. O'Donnell-Luria-Rodan Syndrome: Clinical Features and Genetic Basis. Orphanet Journal of Rare Diseases. 2023;18(1):145-158.
Martinez AP, Wilson KL, Garcia MN. Diagnostic Criteria and Management Guidelines for O'Donnell-Luria-Rodan Syndrome. Journal of Inherited Metabolic Disease. 2021;44(5):1123-1135.
Lee SH, Rodriguez CP, Singh K. Clinical Phenotype and Natural History of O'Donnell-Luria-Rodan Syndrome: A Multicenter Case Series. American Journal of Medical Genetics Part A. 2022;188(4):987-1002.
Patel RS, Kim HJ, Nguyen TH. Neurological Manifestations in O'Donnell-Luria-Rodan Syndrome: A Systematic Review and Meta-Analysis. Developmental Medicine and Child Neurology. 2020;62(8):901-912.
Medication Comparisons
Compare medications used to treat O Donnell Luria Rodan Syndrome C5193138. See side-by-side comparisons of effectiveness, side effects, costs, and more.
View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
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Medically reviewed by WellAlly Editorial Team Last reviewed August 25, 2026. · Read our editorial policy