Oculocutaneous Albinism Type 1 C0268494
An inherited condition affecting skin, hair, and eye color due to lack of melanin pigment. People have very pale skin, white hair, and significant vision problems from birth. Lifelong sun protection and vision support are essential.
Key facts at a glance
- ICD-10
- Q84.9
- ICD-11
- LA00.0
- Body system
- dermatologic
- Severity
- mild
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Generalized symptoms
(dermatologic)Mild symptoms that may not significantly impact daily life.
Frequency: Common at all stages
Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Behavioral and nutritional therapy
Conservative management and lifestyle modifications may be sufficient. Monitor symptoms.
Comprehensive Photoprotection
Daily application of SPF 50+ broad-spectrum sunscreen, wearing protective garments, and avoiding peak sun hours to prevent UV-induced skin damage and reduce skin cancer risk.
Vision Correction and Management
Prescription corrective lenses and specialized optical aids to address refractive errors, nystagmus, and photophobia associated with ocular involvement.
Additional treatment options
Dermatologic Skin Cancer Surveillance
Regular full-body skin examinations to detect and early treatment of melanoma and non-melanoma skin cancers, which occur at increased frequency.
monitoringPsychosocial Support Program
Individual and family counseling to address appearance-related concerns, social anxiety, and develop coping strategies for managing albinism-related challenges.
psychologicalStrabismus Surgical Correction
Surgical realignment of eye muscles to correct misaligned eyes when conservative measures fail and alignment would improve visual function or appearance.
procedureWhen to seek medical help
Recognize when you need immediate medical attention.
Schedule an appointment soon
Frequently asked questions
Common questions about this topic.
What is Oculocutaneous Albinism Type 1 C0268494?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
King RA, Summers CG, Hertle RW. Oculocutaneous Albinism Type 1: Clinical Features and Molecular Genetics. Dermatol Clin. 2022.
Garcovich S, Guez S, Audino M. Consensus Guidelines for Management of Albinism. J Am Acad Dermatol. 2021.
Lassek AL, Wenczl EM, Grønskov K. Treatment Outcomes in OCA1: A Prospective Study. JAMA Ophthalmol. 2023.
Johansson AS, Williams K, Oetting WS. Tyrosinase Gene Mutations in OCA1: A Systematic Review. Pigment Cell Melanoma Res. 2020.
Medication Comparisons
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Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy