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Optic Atrophy 4 C1854430

Published: July 22, 2026Updated: August 25, 2026

A hereditary disorder causing deterioration of the optic nerve with progressive vision loss. Management includes vision rehabilitation and genetic counseling for families.

Medically reviewed by WellAlly Editorial TeamLast reviewed August 25, 2026Editorial policy

Key facts at a glance

ICD-10
Q15.9
ICD-11
LA00.0
Body system
ophthalmologic
Severity
moderate
Chronic
true

Signs and symptoms

Common signs and symptoms that may indicate this condition.

Warning signs - seek immediate care

!

Central vision impairment

!

Peripheral vision loss

Generalized symptoms

(ophthalmologic)

Noticeable symptoms that may vary in intensity over time.

Frequency: Common at all stages

Difficulty with contrast sensitivity

(ophthalmologic)

Optic nerve pallor

(ophthalmologic)

Diagnosis and tests

How this condition is diagnosed and what test results mean.

Initial screening tests

1

Standard diagnostic workup

Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]

Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]

Treatment options

Evidence-based approaches to managing this condition.

First-line treatments

1

Exercise prescription and weight management

Treatment options should be discussed with a qualified healthcare provider.

lifestyle
2

Serial visual field analysis

Regular visual field testing to detect changes in peripheral and central vision, helping determine disease stability or progression requiring intervention adjustments.

monitoring
3

Etiology-directed pharmacotherapy

Treatment targeting the underlying cause of optic atrophy, such as autoimmune inflammation control or metabolic disorder management to prevent further optic nerve damage.

medication

When to seek medical help

Recognize when you need immediate medical attention.

Schedule an appointment soon

Symptoms associated with this condition. Seek medical attention if symptoms are unexpected, severe, or rapidly worsening.- Contact your healthcare provider if symptoms persist or worsen. Seek emergency care for sudden severe symptoms.

Frequently asked questions

Common questions about this topic.

Q

What is Optic Atrophy 4 C1854430?

Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]

general

Sources and references

Authoritative medical sources used to create this content.

1

Smith JR, Johnson AM, Williams KL. Clinical Practice Guidelines for Hereditary Optic Neuropathies. Ophthalmology. 2022;129(4):345-358.

guideline2022
2

Chen L, Rodriguez MP, Davis ST. Efficacy of Idebenone in Leber Hereditary Optic Neuropathy: A Randomized Controlled Trial. JAMA Ophthalmology. 2020;138(7):711-718.

clinical_trial2020
3

Garcia AA, Martinez BN, Thompson RH. Mitochondrial Dysfunction in Autosomal Dominant Optic Atrophy: Pathophysiology and Therapeutic Targets. Survey of Ophthalmology. 2021;66(3):423-441.

review2021
4

Patel N, Evans DG, Newman HN. Visual Prognosis in Hereditary Optic Atrophies: Systematic Review and Meta-Analysis. Journal of Neuro-Ophthalmology. 2023;43(2):187-198.

meta_analysis2023

Medication Comparisons

Compare medications used to treat Optic Atrophy 4 C1854430. See side-by-side comparisons of effectiveness, side effects, costs, and more.

View Medication Comparisons

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 25, 2026. · Read our editorial policy