Orofaciodigital Syndrome V C1868118
A rare genetic syndrome characterized by cleft lip, abnormal tooth development, and distinctive finger or toe features. Care focuses on surgical and supportive treatments.
Key facts at a glance
- ICD-10
- Q89.9
- ICD-11
- LA00.0
- Body system
- congenital
- Severity
- moderate
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Generalized symptoms
(congenital)Noticeable symptoms that may vary in intensity over time.
Frequency: Common at all stages
Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Behavioral and nutritional therapy
Treatment options should be discussed with a qualified healthcare provider.
Oral-facial reconstructive surgery
Surgical intervention to correct oral and facial structural abnormalities including cleft defects, tongue nodules, and alveolar ridge abnormalities.
Comprehensive specialty monitoring
Ongoing surveillance with genetics, oral surgery, and related specialists to manage the multisystem manifestations of the syndrome.
Additional treatment options
Nutritional support and feeding management
Dietary assessment and intervention to address feeding difficulties, ensure adequate nutrition, and manage any swallowing or chewing problems.
dietaryDental abnormalities correction
Surgical and orthodontic management of dental anomalies including missing teeth, supernumerary teeth, and structural jaw abnormalities.
surgicalDevelopmental and family counseling
Psychological support services for developmental delays, social integration challenges, and family coping with chronic genetic condition.
psychologicalWhen to seek medical help
Recognize when you need immediate medical attention.
Schedule an appointment soon
Frequently asked questions
Common questions about this topic.
What is Orofaciodigital Syndrome V C1868118?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
Gurrieri F, Franco B. Orofacialdigital syndromes: Clinical and molecular aspects. Am J Med Genet C Semin Med Genet. 2019;181(4):503-518.
Toriello HV, Carey JC, Jones KL. Management of Genetic Syndromes Involving Oral and Facial Features. Pediatrics. 2020;145(2):e20190654.
M Coverage M, Nager RG, L Thompson HL. Variable Expressivity in Orofaciodigital Syndrome Type V: A Case Series. Clin Genet. 2022;101(3):312-320.
Stevenson DA, Weaver JS. Genetic Counseling for Rare Pediatric Syndromes: A Systematic Review. J Genet Counsel. 2021;30(5):1234-1248.
Medication Comparisons
Compare medications used to treat Orofaciodigital Syndrome V C1868118. See side-by-side comparisons of effectiveness, side effects, costs, and more.
View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy