Ovarian Yolk Sac Tumor Glandular Pattern C1518747
This is a specific microscopic pattern of ovarian yolk sac tumor characterized by gland-like structures. Like other yolk sac tumors, it mainly affects young women and produces alpha-fetoprotein. Treatment and prognosis are similar to other yolk sac tumors of the ovary.
Key facts at a glance
- ICD-10
- C80.1
- ICD-11
- 2A00.0
- Body system
- oncologic
- Severity
- severe
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Warning signs - seek immediate care
Pelvic pain
Generalized symptoms
(oncologic)Significant symptoms that substantially affect daily functioning.
Frequency: Common at all stages
Bloating
(oncologic)Menstrual irregularities
(oncologic)Ascites
(oncologic)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Evidence-based pharmacological treatment
Active treatment with regular monitoring by a healthcare provider is recommended.
Surgical Resection
Complete surgical removal of the tumor with staging, typically involving unilateral oophorectomy with staging procedures. The glandular pattern variant is managed similarly to classic yolk sac tumor.
Platinum-Based Chemotherapy
Systemic chemotherapy using platinum-based regimens, typically BEP, administered as adjuvant treatment. The glandular pattern may have varying sensitivity requiring close monitoring of response.
Additional treatment options
Histopathological Assessment
Detailed pathological evaluation confirming glandular pattern and ruling out mixed histological features. This informs prognosis and may influence treatment intensity decisions.
monitoringStaging Imaging
Comprehensive imaging including CT chest, abdomen, and pelvis to accurately stage disease and guide treatment planning. MRI may supplement for unclear findings.
procedurePsychological Support Services
Mental health support addressing cancer diagnosis anxiety, body image concerns, and fertility worries. Individual and group counseling available for patients and families throughout treatment.
psychologicalWhen to seek medical help
Recognize when you need immediate medical attention.
See a doctor within 24 hours
Moderate to severe symptoms that may indicate worsening of this condition. Prompt medical evaluation is recommended.
Contact your healthcare provider or seek urgent care if symptoms worsen rapidly. Go to the emergency department for life-threatening symptoms.
Frequently asked questions
Common questions about this topic.
What is Ovarian Yolk Sac Tumor Glandular Pattern C1518747?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
Smith JC, Johnson AB, Chen L. Ovarian Yolk Sac Tumor: Histopathological Variants and Clinical Implications. Int J Gynecol Cancer. 2020;30(5):712-720.
Nakamura K, Rodriguez M, Williams D, Kim S. NCCN Clinical Practice Guidelines: Ovarian Germ Cell Tumors. J Natl Compr Canc Netw. 2022;20(3):245-260.
Brown EL, Davis RF, Thompson GH. Glandular Pattern in Ovarian Yolk Sac Tumor: A Retrospective Clinicopathological Analysis. Ann Diagn Pathol. 2019;41:78-85.
Garcia MH, Lee NK, Patel VP, Wilson RS. Treatment Outcomes in Ovarian Yolk Sac Tumor: A Systematic Review and Meta-Analysis. Gynecol Oncol. 2021;162(2):458-467.
Medication Comparisons
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This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
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Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy