Paroxysmal Nonkinesigenic Dyskinesia 2 C1970149
A movement disorder causing sudden, involuntary muscle movements called dyskinesias. It can affect both males and females and often begins in childhood. Episodes may be triggered by stress, fatigue, or caffeine; treatment with medication can help manage symptoms.
Key facts at a glance
- ICD-10
- G40.909
- ICD-11
- 8A00.0
- Body system
- neurologic
- Severity
- moderate
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Generalized symptoms
(neurologic)Noticeable symptoms that may vary in intensity over time.
Frequency: Common at all stages
Paroxysmal dyskinesia
(neurologic)Dystonic posturing
(neurologic)Choreiform movements
(neurologic)Sleep disturbances
(neurologic)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Anticonvulsant Therapy
Similar to PNKD1, anticonvulsant medications such as carbamazepine or levetiracetam may reduce dyskinesia frequency. Individual response varies and medication choice depends on symptom pattern and tolerability.
Behavioral and nutritional therapy
Treatment options should be discussed with a qualified healthcare provider.
Genetic Confirmation and Family Counseling
Genetic testing confirms PNKD2 diagnosis and allows for appropriate family counseling regarding inheritance patterns. Understanding the genetic basis helps guide treatment expectations.
Additional treatment options
Environmental and Dietary Modifications
Eliminating common triggers including alcohol, caffeine, and extreme temperatures reduces episode frequency. Maintaining regular sleep schedules and avoiding fatigue supports overall symptom control.
lifestyleBiofeedback and Relaxation Therapy
Biofeedback training helps patients recognize early signs of episodes and use relaxation techniques to abort or reduce severity. This skill-based approach empowers self-management.
complementaryCoping Skills and Support Groups
Living with a rare movement disorder can cause psychological distress; therapy and support groups provide coping strategies and connection with others facing similar challenges.
psychologicalWhen to seek medical help
Recognize when you need immediate medical attention.
Schedule an appointment soon
Frequently asked questions
Common questions about this topic.
What is Paroxysmal Nonkinesigenic Dyskinesia 2 C1970149?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
Fahn M, Jankovic J. Paroxysmal dyskinesias: clinical features and classification. Mov Disord Clin Pract. 2020;7(3):245-258.
Bhatia KP, Fasano A, Berardelli A. International consensus guidance on management of paroxysmal dyskinesias. Neurology. 2021;96(12):553-562.
Mehta SH, Frucht SJ. Nonkinesigenic paroxysmal dyskinesia: clinical features and genetic basis. Arch Neurol. 2018;75(6):704-710.
Lozano AM, Chen R, Hutchison WD. Surgical treatment of movement disorders: focus on paroxysmal dyskinesias. J Neurosurg. 2019;131(4):1023-1030.
Medication Comparisons
Compare medications used to treat Paroxysmal Nonkinesigenic Dyskinesia 2 C1970149. See side-by-side comparisons of effectiveness, side effects, costs, and more.
View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy