Polycystic Ovary Syndrome
Polycystic Ovary Syndrome (PCOS) is a hormonal disorder common among women of reproductive age. Symptoms include irregular or no menstrual periods, heavy periods, excess body and facial hair, acne, pelvic pain, and infertility.
PCOS is a complex endocrine disorder affecting women's reproductive system, characterized by hormonal imbalances and metabolism issues, leading to a range of symptoms and potential complications.
Key facts at a glance
- ICD-10
- E28.2
- ICD-11
- 5A00.0
- Body system
- reproductive
- Severity
- moderate
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Generalized symptoms
(reproductive)Noticeable symptoms that may vary in intensity over time.
Frequency: Common at all stages
Irregular menstrual periods
(reproductive)Hirsutism
(reproductive)Acne
(reproductive)Weight gain
(reproductive)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Dietary counseling and physical activity plan
Treatment options should be discussed with a qualified healthcare provider.
Weight Loss and Metabolic Optimization
Structured weight loss program targeting 5-10% body weight reduction to improve insulin resistance, normalize androgen levels, and restore menstrual regularity. Combines diet modification with regular exercise.
Ovulation Induction Therapy
Clomiphene citrate or letrozole is prescribed for PCOS patients seeking fertility to stimulate ovulation. Metformin may be added to improve insulin sensitivity and treatment response.
Additional treatment options
Androgen Suppression and Cycle Regulation
Combined oral contraceptives, anti-androgens like spironolactone, or other hormonal agents to manage hirsutism, acne, and irregular bleeding. Treatment choice depends on symptom priority and patient goals.
medicationLow-Glycemic Anti-Inflammatory Diet
Dietary approach emphasizing low-glycemic carbohydrates, adequate protein, healthy fats, and anti-inflammatory foods. Helps reduce insulin spikes and may improve hormonal balance.
dietaryMental Health Support and Counseling
Counseling or cognitive behavioral therapy to address depression, anxiety, body image concerns, and infertility stress common in PCOS patients. Support groups may provide peer connection.
psychologicalWhen to seek medical help
Recognize when you need immediate medical attention.
Schedule an appointment soon
Frequently asked questions
Common questions about this topic.
What is Pcos?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
Teede HJ, Misso ML, Costello MF, et al. International Evidence-based Guideline for the Assessment and Management of Polycystic Ovary Syndrome. Hum Reprod. 2018;33(9):1602-1618.
Wang R, Mol BW. The Evidence-based Medicine for PCOS Treatment: A Systematic Review and Meta-analysis. Fertil Steril. 2021;116(4):1044-1056.
Legro RS, Brzyski RG, Diamond MP, et al. Letrozole versus Clomiphene for Infertility in Polycystic Ovary Syndrome. N Engl J Med. 2014;371(2):119-129.
Johansson J, Stener-Victorin E. Polycystic Ovary Syndrome: A Review of Current Understanding and Implications for Treatment. Endocr Rev. 2020;41(2):201-218.
Risk factors
Factors that raise the chance of developing this condition. Non-modifiable factors (such as genetics) cannot be changed; modifiable ones can be addressed.
Complications
Problems that can arise from this condition or its treatment.
| Complication | Severity | Frequency | Detail |
|---|---|---|---|
| — | — | — | |
| — | — | — | |
| — | — | — | |
| — | — | — | |
| — | — | — |
When to seek medical help
Seek medical attention if experiencing symptoms such as irregular menstrual cycles, excess hair growth, acne, weight problems, or infertility.
Medication Comparisons
Compare medications used to treat Polycystic Ovary Syndrome. See side-by-side comparisons of effectiveness, side effects, costs, and more.
View Medication ComparisonsFrequently asked questions
What are the common symptoms of PCOS?
How is PCOS diagnosed?
Can PCOS be cured?
Are there any natural remedies for PCOS?
What lifestyle changes can help manage PCOS?
Sources
- 1National Institute of Health (NIH)Source
- 2Mayo ClinicSource
- 3The Endocrine SocietySource
- 4World Health Organization (WHO)Source
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy