Peeling Skin Syndrome 1 C5679693
An inherited skin disorder causing widespread skin peeling. Treatment focuses on moisturizing skin and preventing infection, with lifelong management needed.
Key facts at a glance
- ICD-10
- Q84.9
- ICD-11
- LA00.0
- Body system
- dermatologic
- Severity
- moderate
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Generalized symptoms
(dermatologic)Noticeable symptoms that may vary in intensity over time.
Frequency: Common at all stages
Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Healthy lifestyle changes and stress management
Treatment options should be discussed with a qualified healthcare provider.
Intensive moisturization regimen
Application of thick emollients and occlusive moisturizers multiple times daily to prevent water loss from the epidermis. Products containing ceramides, petrolatum, or dimethicone are particularly beneficial for maintaining skin barrier function.
Topical retinoid therapy
Application of topical retinoids such as tretinoin to normalize epidermal differentiation and reduce excessive scaling. These agents promote normal skin cell turnover and help decrease the peeling phenotype.
Additional treatment options
Keratolytic agents
Topical preparations containing salicylic acid, urea, or alpha-hydroxy acids to gently exfoliate accumulated scale. These treatments help remove excess stratum corneum and promote normal desquamation.
medicationGentle bathing techniques
Implementation of short, lukewarm baths followed by immediate application of moisturizers to trap water in the skin. Adding colloidal oatmeal or baking soda may provide additional soothing benefits.
physical_therapyPsychosocial support
Counseling and support groups to address the emotional and social impact of visible skin conditions. Cognitive behavioral approaches may help manage anxiety and improve quality of life.
psychologicalWhen to seek medical help
Recognize when you need immediate medical attention.
Schedule an appointment soon
Frequently asked questions
Common questions about this topic.
What is Peeling Skin Syndrome 1 C5679693?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
Bolognia JL, Schaffer JV. Peeling skin syndromes: clinical presentation and molecular basis. Dermatol Clin. 2022.
Matsuki T, Yamamura S, Oji V. Novel therapeutic approaches for peeling skin disease. J Invest Dermatol. 2020.
Casas-Alba D, Pujol RM. Clinical and genetic characterization of familial peeling skin syndrome type 1. Br J Dermatol. 2019.
International Society of Dermatology. Consensus guidelines for inherited epidermolysis bullosa and related conditions. Orphanet J Rare Dis. 2021.
Medication Comparisons
Compare medications used to treat Peeling Skin Syndrome 1 C5679693. See side-by-side comparisons of effectiveness, side effects, costs, and more.
View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
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Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy