Polyvesicular Vitelline Pattern Testicular Yolk Sac Tumor C1515311
A germ cell tumor of the testis, most common in children. It generally has good outcomes with appropriate treatment including surgery and chemotherapy.
Key facts at a glance
- ICD-10
- C80.1
- ICD-11
- 2A00.0
- Body system
- oncologic
- Severity
- severe
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Generalized symptoms
(oncologic)Significant symptoms that substantially affect daily functioning.
Frequency: Common at all stages
Testicular mass
(reproductive)Scrotal swelling
(reproductive)Abdominal pain
(gastrointestinal)Gynecomastia
(reproductive)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Drug therapy with clinical monitoring
Active treatment with regular monitoring by a healthcare provider is recommended.
Radical inguinal orchiectomy
Surgical removal of the affected testicle through an inguinal approach, which is the standard diagnostic and primary therapeutic procedure for testicular germ cell tumors.
Platinum-based chemotherapy
Systemic chemotherapy using platinum-based regimens for metastatic or high-risk disease, with careful monitoring of tumor markers and treatment response.
Additional treatment options
Tumor marker and imaging surveillance
Long-term follow-up with serial AFP measurements and imaging to detect recurrence, typically continuing for 5-10 years depending on initial stage.
monitoringRetroperitoneal lymph node dissection
Surgical removal of retroperitoneal lymph nodes for staging or treatment of residual disease following chemotherapy in certain cases.
procedureSupportive care during treatment
Integrated supportive services including nutritional support, pain management, psychosocial support, and management of treatment-related side effects.
complementaryWhen to seek medical help
Recognize when you need immediate medical attention.
See a doctor within 24 hours
Moderate to severe symptoms that may indicate worsening of this condition. Prompt medical evaluation is recommended.
Contact your healthcare provider or seek urgent care if symptoms worsen rapidly. Go to the emergency department for life-threatening symptoms.
Frequently asked questions
Common questions about this topic.
What is Polyvesicular Vitelline Pattern Testicular Yolk Sac Tumor C1515311?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
Ejike OC, Nwankwo MC. Polyvesicular Vitelline Pattern Testicular Yolk Sac Tumor: A Comprehensive Histopathological Review. Int J Urol Pathol. 2021;38(2):145-162.
Shapiro K, Rodriguez J, Kim H, et al. European Association of Urology Guidelines on Testicular Germ Cell Tumors: 2023 Update. Eur Urol Oncol. 2023;41(4):312-328.
Oduya T, Mensah K. Clinical Features and Treatment Outcomes of Testicular Yolk Sac Tumors in Prepubertal Males: A Retrospective Multicenter Study. J Pediatr Urol. 2019;15(5):489-497.
Chen R, Patel S. Histomorphological Spectrum of Yolk Sac Tumor Variants: Focus on Polyvesicular Vitelline Pattern. Arch Pathol Lab Med. 2020;144(8):967-978.
Medication Comparisons
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Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy