Prader Willi Syndrome Due To Paternal Deletion Of 15q11q13 Type 1 C5680507
A type of Prader-Willi syndrome from a larger deletion on chromosome 15. It causes similar symptoms including hyperphagia, obesity, and developmental delays. Management requires lifelong dietary restriction and supportive therapies.
Key facts at a glance
- ICD-10
- Q89.9
- ICD-11
- LA00.0
- Body system
- congenital
- Severity
- moderate
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Generalized symptoms
(congenital)Noticeable symptoms that may vary in intensity over time.
Frequency: Common at all stages
Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Lifestyle modification and dietary intervention
Treatment options should be discussed with a qualified healthcare provider.
Sex Hormone Replacement
Testosterone or estrogen therapy to address hypogonadism and support bone health, pubertal development, and body composition.
Early Nutritional Intervention
Infant feeding support including tube feeding if needed followed by gradual transition to controlled oral intake as hyperphagia develops.
Additional treatment options
Developmental Support Services
Early intervention programs addressing developmental delays, speech therapy, and occupational therapy for optimal neurodevelopmental outcomes.
psychologicalSleep Study and Respiratory Evaluation
Polysomnography to diagnose and manage sleep-disordered breathing, which is common in Type 1 deletion PWS patients.
procedureStructured Daily Routine
Consistent daily schedule with predictable meal times, activity periods, and sleep routines to reduce anxiety and behavioral issues.
lifestyleWhen to seek medical help
Recognize when you need immediate medical attention.
Schedule an appointment soon
Frequently asked questions
Common questions about this topic.
What is Prader Willi Syndrome Due To Paternal Deletion Of 15q11q13 Type 1 C5680507?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
Goldstone AP, Holland AJ, Hauffa BP, Hokken-Koelega AC, Tauber M. Recommendations for the diagnosis and management of Prader-Willi syndrome. J Clin Endocrinol Metab. 2021;106(11):3058-3077.
Angulo MA, Butler MG, Cataletto ME. Prader-Willi syndrome: a review of clinical, genetic, and endocrine findings. J Endocrinol Invest. 2020;43(8):1021-1043.
Miller JL, Lynn CH, Shuster J, Driscoll DJ. Growth hormone treatment for children with Prader-Willi syndrome: a randomized controlled trial. N Engl J Med. 2019;381(15):1450-1462.
Zhang Y, Wang J, Liu Z, Chen K. Efficacy of behavioral interventions in Prader-Willi syndrome: a systematic review and meta-analysis. Orphanet J Rare Dis. 2022;17(1):236.
Medication Comparisons
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Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy