Premature Ovarian Failure 9 C3810376
A condition where the ovaries stop working properly before age 40. It mainly affects women and can cause hormonal symptoms and fertility issues. Treatment includes hormone replacement therapy and fertility support.
Key facts at a glance
- ICD-10
- E34.9
- ICD-11
- 5A00.0
- Body system
- endocrine
- Severity
- moderate
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Amenorrhea
(endocrine)Fatigue or weight changes
(endocrine)Noticeable symptoms that may vary in intensity over time.
Frequency: Common at all stages
Weight gain
(endocrine)Dry skin
(endocrine)Hair thinning
(endocrine)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Endocrine management
Treatment options should be discussed with a qualified healthcare provider.
Low-Dose Testosterone Therapy
Adjunctive androgen therapy for persistent fatigue, low libido, and reduced energy despite adequate estrogen replacement. Available as patches or gels.
Stress Reduction and Sleep Hygiene
Implementation of relaxation techniques, mindfulness practices, and sleep optimization strategies to manage insomnia and stress-related symptoms.
Additional treatment options
Cognitive Behavioral Therapy
Structured psychological intervention targeting anxiety, depression, and maladaptive thinking patterns common with chronic health conditions and fertility concerns.
psychologicalComprehensive Hormone Panel
Regular measurement of FSH, estradiol, and other relevant hormones to guide treatment adjustments and assess ovarian function status over time.
monitoringMediterranean Diet Pattern
Anti-inflammatory dietary approach emphasizing olive oil, fish, vegetables, and whole grains to support cardiovascular health and overall wellbeing.
dietaryWhen to seek medical help
Recognize when you need immediate medical attention.
Schedule an appointment soon
Frequently asked questions
Common questions about this topic.
What is Premature Ovarian Failure 9 C3810376?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
Nelson LM, Covington SN, Rosenwaks Z. Clinical practice guideline for the management of primary ovarian insufficiency. Fertil Steril. 2021.
Jankowska K, Durnaś B, Słopień R. Premature ovarian insufficiency: pathogenesis and update on management. Gynecol Endocrinol. 2022.
Webber L, Davies M, Anderson R. European Society for Human Reproduction and Embryology guideline: management of women with premature ovarian insufficiency. Hum Reprod. 2016.
Macklon NS, Fauser BC. Ovarian reserve and follicle dynamics in premature ovarian failure. Ann Endocrinol. 2019.
Medication Comparisons
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View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
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Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy