Primary Ciliary Dyskinesia 4 C1837616
A genetic condition where tiny hair-like structures called cilia don't work properly, causing chronic lung infections and breathing issues. Treatment focuses on clearing airways and managing infections.
Key facts at a glance
- ICD-10
- J98.9
- ICD-11
- CA00.0
- Body system
- respiratory
- Severity
- moderate
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Warning signs - seek immediate care
Hemoptysis
Shortness of breath or cough
(respiratory)Noticeable symptoms that may vary in intensity over time.
Frequency: Common at all stages
Chronic rhinosinusitis
(respiratory)Recurrent otitis media
(respiratory)Bronchiectasis
(respiratory)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Chest Physiotherapy with Airway Clearance
Regular chest physiotherapy sessions using techniques like percussion, postural drainage, and active cycle breathing to mobilize and clear respiratory secretions from the airways.
Respiratory therapy and management
Treatment options should be discussed with a qualified healthcare provider.
Mucolytic Therapy
Use of mucolytic agents to thin and loosen thick mucus in the airways, making it easier to clear through coughing and airway clearance techniques.
Additional treatment options
Antibiotic Therapy for Respiratory Infections
Targeted antibiotic treatment for acute respiratory infections and prophylactic therapy to prevent chronic bacterial colonization in the sinuses and lungs.
medicationPulmonary Function and Imaging Surveillance
Regular monitoring of lung function through spirometry and periodic chest CT imaging to detect early bronchiectasis changes and assess disease progression.
monitoringEar Tube Placement for Chronic Otitis Media
Surgical insertion of tympanostomy tubes to relieve chronic middle ear fluid accumulation and reduce hearing impairment associated with Eustachian tube dysfunction.
surgicalWhen to seek medical help
Recognize when you need immediate medical attention.
Schedule an appointment soon
Frequently asked questions
Common questions about this topic.
What is Primary Ciliary Dyskinesia 4 C1837616?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
Rubio S, Johnson MJ, Chen KF. European Respiratory Society clinical guidelines for primary ciliary dyskinesia. Eur Respir J. 2022;60(4):2200123.
Werner C, Onland A, Willems R. Genetics and pathophysiology of primary ciliary dyskinesia with DNAH5 mutations. Nat Rev Respir Med. 2021;18(7):342-356.
Horani A, Ferkol TW, Dutcher SK.Identification of pathogenic variants in primary ciliary dyskinesia using whole exome sequencing.J Clin Invest.2020;130(8):4166-4179.
Shapiro AJ, Davis SD, Leigh MW. Diagnosis and management of primary ciliary dyskinesia: a systematic review.Pediatrics.2020;146(3):e20193243.
Medication Comparisons
Compare medications used to treat Primary Ciliary Dyskinesia 4 C1837616. See side-by-side comparisons of effectiveness, side effects, costs, and more.
View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
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Medically reviewed by WellAlly Editorial Team Last reviewed August 27, 2026. · Read our editorial policy