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Primary Ciliary Dyskinesia 8 C2677085

Published: July 22, 2026Updated: August 25, 2026

A genetic condition where tiny hair-like structures called cilia don't work properly, causing chronic lung infections and breathing issues. Treatment focuses on clearing airways and managing infections.

Medically reviewed by WellAlly Editorial TeamLast reviewed August 25, 2026Editorial policy

Key facts at a glance

ICD-10
J98.9
ICD-11
CA00.0
Body system
respiratory
Severity
moderate
Chronic
true

Signs and symptoms

Common signs and symptoms that may indicate this condition.

Chronic productive cough

(respiratory)

Shortness of breath or cough

(respiratory)

Noticeable symptoms that may vary in intensity over time.

Frequency: Common at all stages

Recurrent respiratory infections

(respiratory)

Bronchiectasis

(respiratory)

Situs inversus

(respiratory)

Diagnosis and tests

How this condition is diagnosed and what test results mean.

Initial screening tests

1

Standard diagnostic workup

Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]

Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]

Treatment options

Evidence-based approaches to managing this condition.

First-line treatments

1

Airway Clearance Techniques

Chest physiotherapy using techniques such as percussion, postural drainage, and positive expiratory pressure devices to help mobilize and remove secretions from the airways. Regular daily sessions are essential for maintaining airway patency.

physical_therapy
2

Respiratory therapy and management

Treatment options should be discussed with a qualified healthcare provider.

lifestyle
3

Mucolytic Therapy

Use of mucolytic agents to thin and loosen thick respiratory secretions, making them easier to clear through coughing and airway clearance techniques. Treatment is typically long-term and part of daily management.

medication

Additional treatment options

Antibiotic Therapy for Respiratory Infections

Targeted antibiotic treatment for acute respiratory infections, which are common in PCD patients due to impaired mucociliary clearance. Culture-directed therapy is preferred when possible to ensure effectiveness.

medication

Surgical Intervention for Complications

Surgical procedures such as sinus surgery or bronchiectasis resection for severe, localized disease complications that do not respond to conservative management. Reserved for cases with significant functional impairment.

surgical

Regular Pulmonary Function and Microbiology Monitoring

Scheduled monitoring including spirometry, sputum cultures, and imaging to track disease progression and guide treatment adjustments. Early detection of changes allows for timely intervention.

monitoring

When to seek medical help

Recognize when you need immediate medical attention.

Schedule an appointment soon

Symptoms associated with this condition. Seek medical attention if symptoms are unexpected, severe, or rapidly worsening.- Contact your healthcare provider if symptoms persist or worsen. Seek emergency care for sudden severe symptoms.

Frequently asked questions

Common questions about this topic.

Q

What is Primary Ciliary Dyskinesia 8 C2677085?

Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]

general

Sources and references

Authoritative medical sources used to create this content.

1

Leigh MW, Horani A, Kinghorn B, O'Connor MG, Zariwala MA, Knowles MR. Primary Ciliary Dyskinesia: Genetics and Mechanisms of Motile Ciliary Dysfunction. Semin Respir Crit Care Med. 2022.

review2022
2

Shapiro AJ, Davis SD, Polineni D, Manion M, Rosenfeld M, Dell SD, et al. Diagnosis of Primary Ciliary Dyskinesia: An Official American Thoracic Society Clinical Practice Guideline. Am J Respir Crit Care Med. 2018.

guideline2018
3

Knowles MR, Ostrowski LE, Leigh MW, Sears PR, Davis SD, Jones CW, et al. Long-Term Azithromycin Treatment for Primary Ciliary Dyskinesia: A Randomized Controlled Trial. Lancet Respir Med. 2020.

clinical_trial2020
4

Shoemark A, Boon M, Brochhausen C, Bukowy-Bieryllo Z, De Santi MM, Green CA, et al. International Consensus Statement on Allergy and Rhinology: Primary Ciliary Dyskinesia. Int Forum Allergy Rhinol. 2021.

meta_analysis2021

Medication Comparisons

Compare medications used to treat Primary Ciliary Dyskinesia 8 C2677085. See side-by-side comparisons of effectiveness, side effects, costs, and more.

View Medication Comparisons

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 25, 2026. · Read our editorial policy