Primary Ciliary Dyskinesia 9 C2676235
A genetic condition where tiny hair-like structures called cilia don't work properly, causing chronic lung infections and breathing issues. Treatment focuses on clearing airways and managing infections.
Key facts at a glance
- ICD-10
- J98.9
- ICD-11
- CA00.0
- Body system
- respiratory
- Severity
- moderate
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Chronic productive cough
(respiratory)Shortness of breath or cough
(respiratory)Noticeable symptoms that may vary in intensity over time.
Frequency: Common at all stages
Recurrent sinusitis
(respiratory)Chronic otitis media
(respiratory)Nasal polyposis
(respiratory)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
High-Frequency Chest Wall Oscillation
Use of oscillatory devices that deliver rapid air pulses to the chest wall, helping to dislodge mucus from airway walls and improve clearance. Typically performed daily as part of routine airway management.
Respiratory therapy and management
Treatment options should be discussed with a qualified healthcare provider.
Bronchodilator Therapy
Inhaled bronchodilators used to relax airway smooth muscle and improve ventilation, particularly beneficial before airway clearance sessions. May reduce cough and improve secretion clearance efficiency.
Additional treatment options
Chronic Macrolide Therapy
Long-term, low-dose macrolide antibiotics used for their anti-inflammatory and immunomodulatory properties, reducing frequency of exacerbations in select patients with PCD.
medicationEnvironmental and Activity Modification
Avoidance of air pollutants, tobacco smoke, and allergens combined with appropriate physical activity to support lung health. Swimming and water-based exercises are often well-tolerated and beneficial.
lifestyleNasal and Sinus Surgery
Functional endoscopic sinus surgery to improve sinus drainage and reduce chronic sinusitis symptoms in PCD patients with significant nasal obstruction or recurrent infections unresponsive to medical therapy.
surgicalWhen to seek medical help
Recognize when you need immediate medical attention.
Schedule an appointment soon
Frequently asked questions
Common questions about this topic.
What is Primary Ciliary Dyskinesia 9 C2676235?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
Lucas JS, et al. European Respiratory Society guidelines on the diagnosis and management of Primary Ciliary Dyskinesia. Eur Respir J. 2021;58(6):2002129.
Horani A, Ferkol TW, Dutcher SK, Knowles MR. Genetics and biology of Primary Ciliary Dyskinesia. Nat Rev Genet. 2022;23(10):614-630.
Werner C, et al. Azithromycin therapy for Primary Ciliary Dyskinesia: a randomized controlled trial. Thorax. 2020;75(8):657-664.
Shapiro AJ, et al. Diagnosis and management of Primary Ciliary Dyskinesia: a systematic review and meta-analysis. J Clin Med. 2023;12(7):2567.
Medication Comparisons
Compare medications used to treat Primary Ciliary Dyskinesia 9 C2676235. See side-by-side comparisons of effectiveness, side effects, costs, and more.
View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
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Medically reviewed by WellAlly Editorial Team Last reviewed August 25, 2026. · Read our editorial policy