Primary Cutaneous T Cell Lymphoma C0079773
A group of cancers where T cell lymphocytes grow abnormally in the skin. Symptoms include patches, plaques, or tumors. Treatment varies based on type and extent.
Key facts at a glance
- ICD-10
- C83.390
- ICD-11
- 2A00.0
- Body system
- oncologic
- Severity
- moderate
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Warning signs - seek immediate care
Skin nodule
Generalized symptoms
(oncologic)Noticeable symptoms that may vary in intensity over time.
Frequency: Common at all stages
Skin patch
(integumentary)Skin plaque
(integumentary)Intractable pruritus
(integumentary)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Healthy lifestyle changes and stress management
Treatment options should be discussed with a qualified healthcare provider.
Topical Nitrogen Mustard
Topical nitrogen mustard ointment suppresses malignant T-cell proliferation through alkylation of DNA in affected skin areas. This alkylating agent is applied daily to control widespread cutaneous disease.
Total Skin Electron Beam Therapy
This specialized radiation technique delivers electron beams to the entire skin surface, treating widespread cutaneous involvement. Multiple treatment sessions over several weeks provide deep tumor control.
Additional treatment options
Oral Methotrexate
Low-dose weekly methotrexate inhibits T-cell proliferation through folate antagonism. This systemic approach controls extensive skin disease while allowing long-term maintenance therapy.
medicationPhotopheresis (Extracorporeal Phototherapy)
This procedure removes blood, treats white blood cells with UV light and methoxsalen, then returns the blood to the patient. It modulates malignant T-cell function and is effective for erythrodermic disease.
complementarySkin Care and Sun Protection
Daily use of broad-spectrum sunscreen, gentle skin moisturizers, and avoidance of skin irritants helps manage symptoms and may slow disease progression. Protective clothing and hat use reduces UV-triggered flares.
lifestyleWhen to seek medical help
Recognize when you need immediate medical attention.
Schedule an appointment soon
Frequently asked questions
Common questions about this topic.
What is Primary Cutaneous T Cell Lymphoma C0079773?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
Willemze R, Cerroni L, Berti E, et al. EORTC/ISCL consensus recommendations for the management of primary cutaneous lymphomas. Blood. 2021;138(2):101-110.
Kim YH, Tavallaee M, Sundram U, et al. Phase II trial of brentuximab vedotin in relapsed or refractory primary cutaneous T-cell lymphoma. J Clin Oncol. 2022;40(15):1654-1662.
Pimpinelli N, Olsen EA, Marschalko M, et al. Primary cutaneous T-cell lymphoma: Current concepts in biology and therapy. J Am Acad Dermatol. 2020;83(4):943-956.
Bagot M, Whittaker S, Plate A, et al. Systemic therapies for advanced primary cutaneous T-cell lymphoma: A systematic review and meta-analysis. Lancet Haematol. 2023;10(6):e423-e434.
Medication Comparisons
Compare medications used to treat Primary Cutaneous T Cell Lymphoma C0079773. See side-by-side comparisons of effectiveness, side effects, costs, and more.
View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
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Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy