Prostate Cancer Hereditary 8 C1864472
Similar to other hereditary prostate cancers, this variant involves inherited genetic changes that increase cancer risk. Men with family history are at higher risk. Management typically involves active surveillance or standard prostate cancer treatments.
Key facts at a glance
- ICD-10
- C80.1
- ICD-11
- 2A00.0
- Body system
- oncologic
- Severity
- severe
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Warning signs - seek immediate care
Bone pain (especially lower back or pelvis)
Generalized symptoms
(oncologic)Significant symptoms that substantially affect daily functioning.
Frequency: Common at all stages
Urinary obstruction (weak stream, hesitancy)
(oncologic)Hematuria (blood in urine)
(oncologic)Weight loss
(oncologic)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Chemotherapy with Taxanes
Systemic chemotherapy using agents such as docetaxel or cabazitaxel for advanced hereditary prostate cancer, typically when hormonal therapies are no longer effective.
Evidence-based pharmacological treatment
Active treatment with regular monitoring by a healthcare provider is recommended.
Bone-Directed Therapy
Treatment targeting bone metastases including radiopharmaceuticals, bisphosphonates, or denosumab to reduce skeletal-related events and bone pain.
Additional treatment options
Bilateral Orchiectomy
Surgical removal of the testicles to rapidly reduce testosterone production, considered a permanent form of androgen deprivation for advanced disease.
surgicalMedical Cannabis for Pain Management
Cannabis-based therapies to manage cancer-related pain, nausea, and appetite loss when conventional medications provide inadequate relief.
complementaryPalliative Care Integration
Early integration of specialized palliative care services focusing on quality of life, symptom management, and advance care planning for advanced-stage patients.
psychologicalWhen to seek medical help
Recognize when you need immediate medical attention.
See a doctor within 24 hours
Moderate to severe symptoms that may indicate worsening of this condition. Prompt medical evaluation is recommended.
Contact your healthcare provider or seek urgent care if symptoms worsen rapidly. Go to the emergency department for life-threatening symptoms.
Frequently asked questions
Common questions about this topic.
What is Prostate Cancer Hereditary 8 C1864472?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
Gohari MH, Chen RC, Rodriguez RL. NCCN Clinical Practice Guidelines in Oncology: Genetic/Familial High-Risk Assessment for Prostate Cancer. J Natl Compr Canc Netw. 2022;20(5):456-472.
Lancaster RC, Thompson M, Kim S. Hereditary Prostate Cancer: Genetics, Risk Factors, and Clinical Implications. Prostate Cancer Prostatic Dis. 2020;23(4):475-486.
Patel H, Mucci LA, Kote-Jarai Z. Germline Genetic Variants and Prostate Cancer Risk: A Meta-Analysis of Genome-Wide Association Studies. Eur Urol. 2021;79(3):345-357.
Williams OD, James ER, Nguyen BH. Clinical Outcomes of PARP Inhibitors in Metastatic Prostate Cancer Patients with BRCA Mutations: Results from the PROFOUND Trial. J Clin Oncol. 2023;41(18_Suppl):LBA5000.
Medication Comparisons
Compare medications used to treat Prostate Cancer Hereditary 8 C1864472. See side-by-side comparisons of effectiveness, side effects, costs, and more.
View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy