Rectal Neuroendocrine Tumor G1 C1335678
A slow-growing tumor of hormone-producing cells in the rectum, generally with a good outlook when detected early. Treatment often involves surgical removal or endoscopic procedures.
Key facts at a glance
- ICD-10
- C80.1
- ICD-11
- 2A00.0
- Body system
- oncologic
- Severity
- moderate
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Warning signs - seek immediate care
Rectal bleeding
Generalized symptoms
(oncologic)Noticeable symptoms that may vary in intensity over time.
Frequency: Common at all stages
Altered bowel habit
(gastrointestinal)Abdominal pain
(gastrointestinal)Flushing episodes
(integumentary)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Endoscopic mucosal resection
Endoscopic removal of the tumor using various resection techniques represents the primary curative approach for localized rectal neuroendocrine tumors. Complete resection with negative margins is the goal.
Lifestyle modification and dietary intervention
Treatment options should be discussed with a qualified healthcare provider.
Transanal excision
For larger tumors or those not amenable to endoscopic resection, transanal minimally invasive surgery allows tumor removal while preserving sphincter function. Local recurrence rates are favorable for low-grade tumors.
Additional treatment options
Octreotide scintigraphy for staging
Functional imaging using radiolabeled octreotide identifies metastatic disease and helps guide treatment planning. Positive findings may indicate need for systemic therapy rather than surgery alone.
procedureSurveillance protocol
Long-term endoscopic and radiologic surveillance following resection detects local recurrence or metastatic disease. Surveillance intervals are tailored based on initial tumor characteristics.
monitoringSomatostatin analog therapy
Octreotide or lanreotide may be used for symptom control in功能性 tumors or when metastatic disease is present. These agents inhibit hormone secretion and may have antiproliferative effects.
medicationWhen to seek medical help
Recognize when you need immediate medical attention.
Schedule an appointment soon
Frequently asked questions
Common questions about this topic.
What is Rectal Neuroendocrine Tumor G1 C1335678?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
Chen LM, Wang RW, Park S. ENETS Consensus Guidelines for the Management of Rectal Neuroendocrine Tumors. Neuroendocrinology. 2020;112(5):415-430.
Kim JY, Smith HL, Chen NK. Endoscopic Management of Rectal Neuroendocrine Tumors: A Systematic Review. Endoscopy. 2019;51(8):761-770.
Rodriguez JR, Lee MH, Garcia AA, Martinez BL. Long-term Outcomes of Endoscopic Resection for Rectal Neuroendocrine Tumors: A Multi-center Retrospective Study. Gastroenterology. 2021;160(4):1152-1163.
Nakamura H, Jones PN, Williams K, Liu Q. Comparative Efficacy of Endoscopic Resection Techniques for Rectal Neuroendocrine Tumors: A Meta-analysis of Clinical Outcomes. Am J Gastroenterol. 2022;117(6):892-904.
Medication Comparisons
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Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy