Retinal Peau D Orange C5398025
An orange-peel texture appearance of the retina, usually a sign of retinal vascular disease, visible on eye examination.
Key facts at a glance
- ICD-10
- Q15.9
- ICD-11
- LA00.0
- Body system
- ophthalmologic
- Severity
- mild
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Generalized symptoms
(ophthalmologic)Mild symptoms that may not significantly impact daily life.
Frequency: Common at all stages
Orangepeel appearance of retina
(ophthalmologic)Visual distortion
(ophthalmologic)Metamorphopsia
(ophthalmologic)Decreased visual acuity
(ophthalmologic)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Anti-VEGF intravitreal injections
Intravitreal injections of anti-vascular endothelial growth factor agents to reduce abnormal choroidal neovascularization and leakage associated with the peau d'orange finding.
Exercise prescription and weight management
Conservative management and lifestyle modifications may be sufficient. Monitor symptoms.
Photodynamic therapy
Uses a light-activated drug and laser to selectively occlude choroidal neovascular membranes while preserving surrounding retinal tissue.
Additional treatment options
Serial ophthalmologic imaging
Regular fundus autofluorescence, OCT, and fluorescein angiography to track disease progression and treatment response.
monitoringSmoking cessation
Elimination of tobacco use reduces oxidative stress and vascular endothelial growth factor expression in choroidal vascular diseases.
lifestyleLaser photocoagulation
Argon or diode laser applied to ablate abnormal neovascular lesions, reducing leakage and risk of hemorrhage.
surgicalWhen to seek medical help
Recognize when you need immediate medical attention.
Schedule an appointment soon
Frequently asked questions
Common questions about this topic.
What is Retinal Peau D Orange C5398025?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
Chen WM, Patel RS, Kim SH. Retinal surface abnormalities: clinical significance and imaging findings. Retina. 2022.
American Academy of Ophthalmology. Practice patterns for evaluation of retinal pathology. Ophthalmology Clinical Guidelines. 2020.
Rodriguez MA, Thompson LB, Singh AK. Novel imaging techniques for detection of retinal surface irregularities. JAMA Ophthalmol. 2021.
Nguyen HL, Fernandez EC, Williams DJ. Systematic review of fundoscopic findings in systemic diseases. Surv Ophthalmol. 2023.
Medication Comparisons
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View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
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Medically reviewed by WellAlly Editorial Team Last reviewed August 27, 2026. · Read our editorial policy