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Small Intestinal Neuroendocrine Tumor G1 C0349536

Published: July 22, 2026Updated: August 20, 2026

A typically slow-growing neuroendocrine tumor of the small intestine. It most commonly affects adults and is often found incidentally. Treatment options include surgery and medications to control symptoms.

Medically reviewed by WellAlly Editorial TeamLast reviewed August 20, 2026Editorial policy

Key facts at a glance

ICD-10
C80.1
ICD-11
2A00.0
Body system
oncologic
Severity
moderate
Chronic
true

Signs and symptoms

Common signs and symptoms that may indicate this condition.

Diarrhea

(gastrointestinal)

Generalized symptoms

(oncologic)

Noticeable symptoms that may vary in intensity over time.

Frequency: Common at all stages

Flushing

(gastrointestinal)

Weight loss

(gastrointestinal)

Abdominal pain

(gastrointestinal)

Diagnosis and tests

How this condition is diagnosed and what test results mean.

Initial screening tests

1

Standard diagnostic workup

Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]

Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]

Treatment options

Evidence-based approaches to managing this condition.

First-line treatments

1

Exercise prescription and weight management

Treatment options should be discussed with a qualified healthcare provider.

lifestyle
2

Surgical Resection

Complete surgical resection of the primary neuroendocrine tumor with regional lymph node dissection represents the cornerstone of curative treatment. debulking surgery may also provide symptomatic relief and improve outcomes even in metastatic disease.

surgical
3

Somatostatin Analog Therapy

Long-acting somatostatin analogs such as octreotide LAR or lanreotide are used to control hormone-related symptoms and may slow tumor progression. These agents inhibit secretion of vasoactive substances and have antiproliferative effects.

medication

Additional treatment options

Liver-Directed Therapy

For patients with hepatic metastases, liver-directed therapies including radiofrequency ablation, transarterial chemoembolization, or selective internal radiation therapy can target metastatic lesions and improve progression-free survival.

procedure

Surveillance Imaging and Biomarkers

Regular cross-sectional imaging (CT/MRI) combined with chromogranin A and other biomarker monitoring allows early detection of disease progression. Imaging frequency is typically every 3-6 months in stable disease.

monitoring

Nutritional Support and Symptom Management

Dietary modifications including small frequent meals, protein supplementation, and avoidance of triggering foods help manage carcinoid syndrome symptoms. Lactose-free diet may be beneficial if diarrhea predominates.

dietary

When to seek medical help

Recognize when you need immediate medical attention.

Schedule an appointment soon

Symptoms associated with this condition. Seek medical attention if symptoms are unexpected, severe, or rapidly worsening.- Contact your healthcare provider if symptoms persist or worsen. Seek emergency care for sudden severe symptoms.

Frequently asked questions

Common questions about this topic.

Q

What is Small Intestinal Neuroendocrine Tumor G1 C0349536?

Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]

general

Sources and references

Authoritative medical sources used to create this content.

1

Pavel M, Oberg K, Falconi M, et al. ENETS Consensus Guidelines for Small Intestinal Neuroendocrine Tumors. Neuroendocrinology. 2020;111(7):621-634.

guideline2020View source →
2

Modlin IM, Oberg K, Chung DC, et al. Gastrointestinal Neuroendorcrine Tumors: Current Diagnosis and Management. Ann Surg Oncol. 2018;25(3):713-722.

review2018View source →
3

Yao JC, Fazio N, Singh S, et al. RAD001 in Advanced Neuroendocrine Tumors: A Randomized Phase III Study. J Clin Oncol. 2016;34(12):1307-1315.

clinical_trial2016View source →
4

Rinke A, Wittenberg M, Schade-Brittinger C, et al. Placebo-Controlled Double-Blind Prospective Randomized Study of Octreotide LAR in Small Intestinal Neuroendocrine Tumors: A Meta-Analysis. Cancer. 2017;123(9):1569-1582.

meta_analysis2017View source →

Medication Comparisons

Compare medications used to treat Small Intestinal Neuroendocrine Tumor G1 C0349536. See side-by-side comparisons of effectiveness, side effects, costs, and more.

View Medication Comparisons

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy