Spermatogenic Failure 77 C5774245
This genetic form of male infertility results from abnormal sperm cell development in the testes. Affected individuals may benefit from fertility specialist consultation and assisted conception methods.
Key facts at a glance
- ICD-10
- Q55.9
- ICD-11
- LA00.0
- Body system
- reproductive
- Severity
- severe
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Generalized symptoms
(reproductive)Significant symptoms that substantially affect daily functioning.
Frequency: Common at all stages
Infertility
(reproductive)Semen volume reduction
(reproductive)Reduced sperm motility
(reproductive)Teratozoospermia
(reproductive)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Hormonal Therapy with Clomiphene Citrate
Clomiphene citrate acts as a selective estrogen receptor modulator to increase gonadotropin release, stimulating spermatogenesis. This oral medication is typically prescribed for cases with hypogonadotropic hypogonadism.
Medication management with follow-up care
Active treatment with regular monitoring by a healthcare provider is recommended.
Heat Avoidance and Scrotal Cooling
Eliminating exposure to heat sources including hot tubs, saunas, tight underwear, and prolonged sitting to maintain optimal scrotal temperature for sperm production.
Additional treatment options
Antioxidant Supplementation
Comprehensive antioxidant regimen including vitamins C, E, selenium, zinc, and coenzyme Q10 to reduce oxidative stress and improve sperm quality parameters.
dietaryVaricocele Repair
Surgical correction of varicocele when present, using microsurgical varicocelectomy technique to improve testicular blood flow and sperm production.
surgicalAcupuncture Therapy
Traditional Chinese medicine approach using acupuncture to improve testicular function and balance hormonal levels, often combined with other treatments.
complementaryWhen to seek medical help
Recognize when you need immediate medical attention.
See a doctor within 24 hours
Moderate to severe symptoms that may indicate worsening of this condition. Prompt medical evaluation is recommended.
Contact your healthcare provider or seek urgent care if symptoms worsen rapidly. Go to the emergency department for life-threatening symptoms.
Frequently asked questions
Common questions about this topic.
What is Spermatogenic Failure 77 C5774245?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
Krausz C, Riera-Escamilla A. Genetics of male infertility: from research to clinical practice. Nat Rev Urol. 2022.
American Urological Association. Male Infertility: AUA Guideline. J Urol. 2020.
Liu Y, Chen J, Wang X, Zhang L. Novel biallelic mutations in meiosis-related genes cause spermatogenic failure. Hum Reprod. 2021.
Shahrokhi SZ, Salehi P, Hamed P. Genetic causes of non-obstructive azoospermia: a systematic review. Andrology. 2022.
Medication Comparisons
Compare medications used to treat Spermatogenic Failure 77 C5774245. See side-by-side comparisons of effectiveness, side effects, costs, and more.
View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
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Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy