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Spermatogenic Failure 79 C5774290

Published: July 22, 2026Updated: August 20, 2026

A genetic disorder that disrupts the normal sperm development process in the testes, leading to male infertility. Assisted reproductive technologies may help some affected individuals father children.

Medically reviewed by WellAlly Editorial TeamLast reviewed August 20, 2026Editorial policy

Key facts at a glance

ICD-10
Q55.9
ICD-11
LA00.0
Body system
reproductive
Severity
severe
Chronic
true

Signs and symptoms

Common signs and symptoms that may indicate this condition.

Generalized symptoms

(reproductive)

Significant symptoms that substantially affect daily functioning.

Frequency: Common at all stages

Infertility

(reproductive)

Low semen volume

(reproductive)

Decreased libido

(reproductive)

Testicular atrophy

(reproductive)

Diagnosis and tests

How this condition is diagnosed and what test results mean.

Initial screening tests

1

Standard diagnostic workup

Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]

Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]

Treatment options

Evidence-based approaches to managing this condition.

First-line treatments

1

FSH (Follicle-Stimulating Hormone) Therapy

Recombinant FSH administration to directly stimulate Sertoli cells and germ cell development in men with impaired gonadotropin stimulation.

medication
2

Pharmacological management with first-line agents

Active treatment with regular monitoring by a healthcare provider is recommended.

medication
3

Structured Exercise Program

Moderate-intensity regular exercise regimen to improve hormonal balance, reduce obesity, and enhance overall reproductive health.

lifestyle

Additional treatment options

Fertility Counseling and Support

Psychological support addressing emotional stress, relationship strain, and depression commonly associated with male factor infertility diagnosis.

psychological

Mediterranean Diet Modification

Adoption of Mediterranean dietary pattern rich in omega-3 fatty acids, antioxidants, and whole grains to support sperm membrane integrity and function.

dietary

Herbal Supplement Therapy with Fenugreek

Standardized fenugreek seed extract supplementation shown in studies to modestly improve testosterone levels and sperm parameters.

complementary

When to seek medical help

Recognize when you need immediate medical attention.

See a doctor within 24 hours

Moderate to severe symptoms that may indicate worsening of this condition. Prompt medical evaluation is recommended.

Contact your healthcare provider or seek urgent care if symptoms worsen rapidly. Go to the emergency department for life-threatening symptoms.

Frequently asked questions

Common questions about this topic.

Q

What is Spermatogenic Failure 79 C5774290?

Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]

general

Sources and references

Authoritative medical sources used to create this content.

1

Krausz C, Cioppi F, Riera-Escamilla A. Genetic factors of non-obstructive azoospermia: consequences for clinical management. Andrology. 2018.

review2018
2

Jungwirth A, Giwereman A, Kokkoris E, et al. European Association of Urology Guidelines on Male Infertility. Eur Urol. 2022.

guideline2022
3

Aston KI, Conrad DF. A review of altered recombination and mutation in human male infertility. Reproduction. 2013.

other2013
4

Sun K, Chen L, Wang Y, et al. Association between genetic variants and male infertility: a systematic review and meta-analysis. Fertil Steril. 2021.

meta_analysis2021

Medication Comparisons

Compare medications used to treat Spermatogenic Failure 79 C5774290. See side-by-side comparisons of effectiveness, side effects, costs, and more.

View Medication Comparisons

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy