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Spermatogenic Failure 86 C5882755

Published: July 22, 2026Updated: August 20, 2026

A genetic variant affecting sperm cell development, causing male infertility. Assisted reproduction may be considered.

Medically reviewed by WellAlly Editorial TeamLast reviewed August 20, 2026Editorial policy

Key facts at a glance

ICD-10
Q55.9
ICD-11
LA00.0
Body system
reproductive
Severity
severe
Chronic
true

Signs and symptoms

Common signs and symptoms that may indicate this condition.

Generalized symptoms

(reproductive)

Significant symptoms that substantially affect daily functioning.

Frequency: Common at all stages

Subfertility

(reproductive)

Low sperm concentration

(reproductive)

Teratospermia

(reproductive)

Elevated FSH levels

(reproductive)

Diagnosis and tests

How this condition is diagnosed and what test results mean.

Initial screening tests

1

Standard diagnostic workup

Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]

Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]

Treatment options

Evidence-based approaches to managing this condition.

First-line treatments

1

Medication management with follow-up care

Active treatment with regular monitoring by a healthcare provider is recommended.

medication
2

Selective Estrogen Receptor Modulators (SERMs)

Tamoxifen or clomiphene citrate to block estrogen negative feedback and increase gonadotropin secretion for enhanced spermatogenesis.

medication
3

Micro-TESE

Microsurgical testicular sperm extraction using optical magnification to identify and retrieve sperm-producing tubules with higher yield.

procedure

Additional treatment options

Traditional Chinese Medicine

Acupuncture and herbal formulations aimed at improving testicular function through traditional meridian theory and herbal pharmacology.

complementary

Serial Semen Analysis

Regular monitoring of semen parameters over time to assess disease progression, treatment response, and reproductive potential.

monitoring

Mediterranean Diet Optimization

Nutritional intervention emphasizing omega-3 fatty acids, antioxidants, and whole foods while reducing processed foods and saturated fats.

dietary

When to seek medical help

Recognize when you need immediate medical attention.

See a doctor within 24 hours

Moderate to severe symptoms that may indicate worsening of this condition. Prompt medical evaluation is recommended.

Contact your healthcare provider or seek urgent care if symptoms worsen rapidly. Go to the emergency department for life-threatening symptoms.

Frequently asked questions

Common questions about this topic.

Q

What is Spermatogenic Failure 86 C5882755?

Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]

general

Sources and references

Authoritative medical sources used to create this content.

1

Jungwirth A, Giwereman A, Tourmaye H. European Association of Urology Guidelines on Male Infertility. Eur Urol. 2022.

guideline2022View source →
2

Krausz C, Riera-Escamilla A, Chianese C. Genetics of Male Infertility: From SYCP2 to SPATA6. Hum Reprod Update. 2021.

review2021View source →
3

Tüttelmann F, Wyrwoll MJ, Wöste LM. Genetic Characterization of Spermatogenic Failure in Consanguineous Families. Andrology. 2023.

clinical_trial2023View source →
4

Ahmadi Z, Gholizadeh L, Sadeghi MR. Association Between Genetic Variants and Non-Obstructive Azoospermia: A Systematic Review. J Assist Reprod Genet. 2020.

meta_analysis2020View source →

Medication Comparisons

Compare medications used to treat Spermatogenic Failure 86 C5882755. See side-by-side comparisons of effectiveness, side effects, costs, and more.

View Medication Comparisons

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy