Spermatogenic Failure 9 C3151407
A genetic condition causing absent or severely reduced sperm production, resulting in male infertility. These cases typically require assisted reproductive technology for conception.
Key facts at a glance
- ICD-10
- Q55.9
- ICD-11
- LA00.0
- Body system
- reproductive
- Severity
- severe
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Generalized symptoms
(reproductive)Significant symptoms that substantially affect daily functioning.
Frequency: Common at all stages
Infertility
(reproductive)Erectile dysfunction
(reproductive)Reduced sperm motility
(reproductive)Gynecomastia
(reproductive)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Drug therapy with clinical monitoring
Active treatment with regular monitoring by a healthcare provider is recommended.
Letrozole Treatment
Aromatase inhibitor that reduces estrogen and increases testosterone production in men with spermatogenic failure. Particularly useful in obese patients with elevated estrogen.
Weight Management Program
Structured program targeting healthy body weight through balanced nutrition and regular exercise. Obesity negatively impacts hormone levels and sperm production.
Additional treatment options
Testicular Sperm Aspiration (TESA)
Minimally invasive procedure to retrieve sperm directly from testicular tissue using fine needle aspiration. Often combined with intracytoplasmic sperm injection (ICSI).
procedureMediterranean Diet Protocol
Adoption of Mediterranean dietary pattern emphasizing omega-3 fatty acids, fresh vegetables, fruits, and whole grains while reducing processed foods and saturated fats.
dietaryFertility Counseling
Psychological support addressing the emotional impact of infertility diagnosis. Includes coping strategies, communication skills, and decision-making guidance for treatment options.
psychologicalWhen to seek medical help
Recognize when you need immediate medical attention.
See a doctor within 24 hours
Moderate to severe symptoms that may indicate worsening of this condition. Prompt medical evaluation is recommended.
Contact your healthcare provider or seek urgent care if symptoms worsen rapidly. Go to the emergency department for life-threatening symptoms.
Frequently asked questions
Common questions about this topic.
What is Spermatogenic Failure 9 C3151407?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
Krausz C, Tüttelmann F, Arévalo ML. EAA/EMQN best practice guidelines for molecular diagnosis of Y-chromosomal microdeletions and sertoli cell-only syndrome. Int J Androl. 2020.
Silva JV, Dôpoest L, Sousa M. Genetic causes of non-obstructive azoospermia: a systematic review. Andrology. 2021.
Stouffs K, Gheldof A, Touré E. Molecular screening of azoospermia factor region deletions in infertile men: a cohort study. J Assist Reprod Genet. 2019.
Nuti F, Bach PV, Sakkas D. Role of genetic mutations in male infertility: a meta-analysis of candidate gene studies. Hum Reprod Update. 2022.
Medication Comparisons
Compare medications used to treat Spermatogenic Failure 9 C3151407. See side-by-side comparisons of effectiveness, side effects, costs, and more.
View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy