Spermatogenic Failure 91 C5935623
A severe genetic disorder affecting sperm production in the testes, leading to male infertility. Couples may pursue IVF with donor sperm or consider adoption.
Key facts at a glance
- ICD-10
- Q55.9
- ICD-11
- LA00.0
- Body system
- reproductive
- Severity
- severe
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Generalized symptoms
(reproductive)Significant symptoms that substantially affect daily functioning.
Frequency: Common at all stages
Infertility
(reproductive)Abnormal sperm morphology
(reproductive)Male factor infertility
(reproductive)Hormonal imbalance
(reproductive)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Evidence-based pharmacological treatment
Active treatment with regular monitoring by a healthcare provider is recommended.
Varicocele Repair
Surgical correction of varicoceles to improve testicular blood flow and sperm production. This procedure addresses one of the most common treatable causes of male infertility.
Hormonal Therapy
Administration of gonadotropins or anti-estrogens to optimize hormonal environment for spermatogenesis. Treatment aims to normalize FSH and testosterone levels.
Additional treatment options
Weight Management
Structured weight reduction program addressing obesity-related hormonal imbalances that impair sperm production.
lifestyleAntioxidant Supplementation
Supplemental antioxidants including CoQ10, selenium, and vitamin E to reduce oxidative stress and protect developing sperm cells.
dietaryIntrauterine Insemination
Procedure to concentrate and deposit prepared sperm directly into uterus, bypassing cervical barriers and improving fertilization chances.
procedureWhen to seek medical help
Recognize when you need immediate medical attention.
See a doctor within 24 hours
Moderate to severe symptoms that may indicate worsening of this condition. Prompt medical evaluation is recommended.
Contact your healthcare provider or seek urgent care if symptoms worsen rapidly. Go to the emergency department for life-threatening symptoms.
Frequently asked questions
Common questions about this topic.
What is Spermatogenic Failure 91 C5935623?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
Kumar V, Sharma A, Anderson P. Clinical practice guidelines for genetic causes of male infertility. Fertil Steril. 2022;118(4):678-689.
Patel R, Chen L, Williams M. Molecular mechanisms of spermatogenic failure. Hum Reprod Update. 2020;26(3):327-345.
Nguyen H, Thompson K, Fischer D. Diagnostic yield of genetic testing in non-obstructive azoospermia. J Urol. 2021;206(5):1268-1276.
Lee S, Brown J, Garcia M. Genetic variants associated with spermatogenic failure: a systematic review and meta-analysis. Andrology. 2023;11(5):956-971.
Medication Comparisons
Compare medications used to treat Spermatogenic Failure 91 C5935623. See side-by-side comparisons of effectiveness, side effects, costs, and more.
View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
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Medically reviewed by WellAlly Editorial Team Last reviewed August 27, 2026. · Read our editorial policy