Spermatogenic Failure 98 C6012703
A form of male infertility caused by genetic mutations that impair the development of sperm cells. Men with this condition typically require fertility treatments to conceive.
Key facts at a glance
- ICD-10
- Q55.9
- ICD-11
- LA00.0
- Body system
- reproductive
- Severity
- severe
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Azoospermia (absence of sperm)
(reproductive)Generalized symptoms
(reproductive)Significant symptoms that substantially affect daily functioning.
Frequency: Common at all stages
Asthenozoospermia (reduced sperm motility)
(reproductive)Elevated FSH (hypergonadotropic state)
(reproductive)Erectile dysfunction
(reproductive)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Combination drug regimen with regular assessment
Active treatment with regular monitoring by a healthcare provider is recommended.
Follicle-Stimulating Hormone (FSH) Therapy
Recombinant FSH administration to directly stimulate Sertoli cells and promote spermatogenesis in men with primary testicular failure or FSH deficiency.
Testicular Microdissection TESE
Microdissection technique minimizing testicular tissue damage while maximizing sperm retrieval rates in severe non-obstructive azoospermia cases.
Additional treatment options
Smoking Cessation Program
Structured tobacco cessation including behavioral support and pharmacotherapy to eliminate smoking-related oxidative stress and toxic effects on sperm DNA integrity.
lifestyleAcupuncture for Male Fertility
Traditional acupuncture protocols targeting reproductive meridians to improve testicular blood flow, reduce stress, and potentially enhance sperm quality parameters.
complementaryGenetic Counseling and Karyotype Analysis
Comprehensive genetic evaluation to identify chromosomal abnormalities, Y-chromosome microdeletions, or heritable conditions affecting spermatogenesis and offspring risk.
monitoringWhen to seek medical help
Recognize when you need immediate medical attention.
See a doctor within 24 hours
Moderate to severe symptoms that may indicate worsening of this condition. Prompt medical evaluation is recommended.
Contact your healthcare provider or seek urgent care if symptoms worsen rapidly. Go to the emergency department for life-threatening symptoms.
Frequently asked questions
Common questions about this topic.
What is Spermatogenic Failure 98 C6012703?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
Jungwirth A, Diemer T, Kopa Z, et al. European Association of Urology Guidelines on Male Infertility. Eur Urol. 2022.
Krausz C, Chianese C, Giachini RM, et al. The Genetic Basis of Human Spermatogenic Failure. Hum Reprod Update. 2020.
Santi D, Spaggiari G, Casarini L, et al. Testosterone Treatment Outcomes in Hypogonadal Men with Spermatogenic Failure: A Systematic Review and Meta-Analysis. J Clin Endocrinol Metab. 2021.
Aston KI, Carrell DT. Genomics and Proteomics in Reproductive Medicine. Fertil Steril. 2019.
Medication Comparisons
Compare medications used to treat Spermatogenic Failure 98 C6012703. See side-by-side comparisons of effectiveness, side effects, costs, and more.
View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy