St2 Diffuse Large B Cell Lymphoma C5707084
An aggressive form of large B-cell lymphoma affecting lymphoid tissue. Requires prompt cancer treatment with chemotherapy and may involve targeted therapies.
Key facts at a glance
- ICD-10
- C83.37
- ICD-11
- 2A00.0
- Body system
- oncologic
- Severity
- severe
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Generalized symptoms
(oncologic)Significant symptoms that substantially affect daily functioning.
Frequency: Common at all stages
Painless lymphadenopathy
(oncologic)B symptoms (fever, night sweats, weight loss)
(oncologic)Fatigue
(oncologic)Abdominal fullness or pain from organ involvement
(oncologic)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Immunochemotherapy (R-CHOP)
Combination immunotherapy with rituximab and cyclophosphamide, doxorubicin, vincristine, and prednisone targeting cancer cells and the immune system.
Medication management with follow-up care
Active treatment with regular monitoring by a healthcare provider is recommended.
Additional treatment options
Radiation Therapy
Targeted radiation to destroy cancer cells, often used for localized disease or palliative symptom relief in advanced cases.
procedureAutologous Stem Cell Transplant
High-dose chemotherapy followed by reinfusion of patient's own stem cells to restore bone marrow function after intensive treatment.
surgicalSurveillance Imaging
Regular PET-CT or CT scans to monitor treatment response, detect recurrence, and assess disease progression.
monitoringSupportive Care
Multidisciplinary approach including pain management, nutritional support, and psychosocial services to improve quality of life during treatment.
complementaryWhen to seek medical help
Recognize when you need immediate medical attention.
See a doctor within 24 hours
Moderate to severe symptoms that may indicate worsening of this condition. Prompt medical evaluation is recommended.
Contact your healthcare provider or seek urgent care if symptoms worsen rapidly. Go to the emergency department for life-threatening symptoms.
Frequently asked questions
Common questions about this topic.
What is St2 Diffuse Large B Cell Lymphoma C5707084?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
Zelenetz AD, Abramson JS, Advani RH, et al. NCCN Clinical Practice Guidelines in Oncology: B-Cell Lymphomas Version 3.2023. J Natl Compr Canc Netw. 2023.
Sehn LH, Hertzberg MT, MacManus MP, et al. Polatuzumab Vedotin plus Rituximab, Cyclophosphamide, Doxorubicin, and Prednisone in Previously Untreated Diffuse Large B-Cell Lymphoma: Primary Analysis of the Phase III POLARIX Trial. J Clin Oncol. 2022.
Swerdlow SH, Campo E, Harris NL, et al. Diffuse Large B-Cell Lymphoma: Pathology and Molecular Classification. Blood Rev. 2020.
Guan Y, Li Q, Xiao Q, et al. CAR T-Cell Therapy for Relapsed or Refractory Diffuse Large B-Cell Lymphoma: A Systematic Review and Meta-Analysis. Haematologica. 2023.
Medication Comparisons
Compare medications used to treat St2 Diffuse Large B Cell Lymphoma C5707084. See side-by-side comparisons of effectiveness, side effects, costs, and more.
View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy