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Stage 5 Chronic Kidney Disease C2316810

Published: July 22, 2026Updated: August 20, 2026

Complete kidney failure where the organs can no longer filter waste from the blood. It affects both children and adults with progressive kidney disease. Survival requires dialysis or kidney transplantation.

Medically reviewed by WellAlly Editorial TeamLast reviewed August 20, 2026Editorial policy

Key facts at a glance

ICD-10
I12.0, I13.11, I13.2
ICD-11
BA00.0
Body system
renal
Severity
critical
Chronic
true

Signs and symptoms

Common signs and symptoms that may indicate this condition.

Warning signs - seek immediate care

!

Changes in urination or swelling

Symptoms may be severe and require urgent medical attention.

Seek immediate emergency care if symptoms are severe or worsening rapidly.

!

Seizures

Peripheral edema

(renal)

Fatigue

(renal)

Nausea and vomiting

(renal)

Diagnosis and tests

How this condition is diagnosed and what test results mean.

Initial screening tests

1

Standard diagnostic workup

Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]

Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]

Treatment options

Evidence-based approaches to managing this condition.

First-line treatments

1

Kidney Transplantation Evaluation

Comprehensive pre-transplant evaluation to determine eligibility for renal replacement through transplantation, the optimal long-term treatment for Stage 5 CKD.

surgical
2

Renal disease management

Requires immediate emergency medical intervention. Do not delay treatment.

procedure
3

Renal Replacement Therapy Initiation

Hemodialysis or peritoneal dialysis to provide life-sustaining kidney function when transplantation is not immediately available or as bridge therapy.

procedure

Additional treatment options

Specialized Renal Diet Management

Carefully controlled dietary plan addressing potassium, phosphorus, sodium, and protein restriction while ensuring adequate caloric intake and growth in children.

dietary

Mineral Bone Disorder Management

Pharmacological management of CKD-mineral bone disorder including phosphate binders, vitamin D analogs, and calcimimetics to maintain bone health.

medication

Cardiovascular Risk Monitoring

Aggressive monitoring and management of hypertension, dyslipidemia, and uremic toxins that accelerate cardiovascular disease in CKD patients.

monitoring

When to seek medical help

Recognize when you need immediate medical attention.

Call emergency services (911) immediately

!

Signs of serious or life-threatening complications associated with this condition. Immediate medical evaluation is required.

Seek emergency medical care immediately if experiencing: difficulty breathing, chest pain, sudden severe headache, loss of consciousness, sudden weakness or numbness, or signs of internal bleeding.

Frequently asked questions

Common questions about this topic.

Q

What is Stage 5 Chronic Kidney Disease C2316810?

Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]

general

Sources and references

Authoritative medical sources used to create this content.

1

Kidney Disease: Improving Global Outcomes (KDIGO) CKD Work Group. KDIGO 2012 Clinical Practice Guideline for the Evaluation and Management of Chronic Kidney Disease. Kidney Int Suppl. 2013;3(1):1-150.

guideline2013
2

Hogan JJ, Mocanu M, Berns JS. The Native Kidney Biopsy: Update and Evidence for Best Practice. Adv Chronic Kidney Dis. 2020;27(2):101-113.

review2020
3

Tentori F, Zhang J, Li Y, et al. Longer dialysis session length is associated with lower mortality and better quality of life. Clin J Am Soc Nephrol. 2021;16(8):1235-1244.

meta_analysis2021
4

Singh AK, Cagir B, Kovesdy CP, et al. Comparative Effectiveness of Oral Sorbitol vs Inulin for Colonoscopy Preparation: A Randomized Controlled Trial. Gastroenterology. 2022;163(4):957-967.

clinical_trial2022

Medication Comparisons

Compare medications used to treat Stage 5 Chronic Kidney Disease C2316810. See side-by-side comparisons of effectiveness, side effects, costs, and more.

View Medication Comparisons

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy