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Tertiary Lesion Of Yaws C0343833

Published: July 22, 2026Updated: August 27, 2026

Yaws is a tropical bacterial skin infection affecting children in warm climates. Tertiary lesions develop years later, damaging skin, bone, and cartilage. Penicillin antibiotics treat the infection effectively.

Medically reviewed by WellAlly Editorial TeamLast reviewed August 27, 2026Editorial policy

Key facts at a glance

ICD-10
A66.0, A66.2
ICD-11
1A00.0
Body system
infectious
Severity
moderate
Chronic
true

Signs and symptoms

Common signs and symptoms that may indicate this condition.

Fever or malaise

(infectious)

Noticeable symptoms that may vary in intensity over time.

Frequency: Common at all stages

Diagnosis and tests

How this condition is diagnosed and what test results mean.

Initial screening tests

1

Standard diagnostic workup

Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]

Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]

Treatment options

Evidence-based approaches to managing this condition.

First-line treatments

1

Antimicrobial or antiviral therapy

Treatment options should be discussed with a qualified healthcare provider.

lifestyle
2

Long-acting penicillin therapy

Intramuscular benzathine penicillin G injection targeting treponemal infection causing tertiary manifestations including gummatous lesions.

medication
3

Serological follow-up testing

Regular non-treponemal and treponemal testing to assess treatment response and detect reinfection in tertiary-stage disease.

monitoring

Additional treatment options

Doxycycline alternative regimen

For penicillin-allergic patients, doxycycline provides alternative antimicrobial coverage against treponemal organisms.

medication

Surgical intervention for gummas

Excision or debridement of destructive gummatous tissue causing functional impairment or cosmetic concern when medical therapy insufficient.

procedure

Contact tracing and partner notification

Identification and evaluation of sexual contacts for potential infection and treatment to prevent ongoing transmission.

lifestyle

When to seek medical help

Recognize when you need immediate medical attention.

Schedule an appointment soon

Symptoms associated with this condition. Seek medical attention if symptoms are unexpected, severe, or rapidly worsening.- Contact your healthcare provider if symptoms persist or worsen. Seek emergency care for sudden severe symptoms.

Frequently asked questions

Common questions about this topic.

Q

What is Tertiary Lesion Of Yaws C0343833?

Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]

general

Sources and references

Authoritative medical sources used to create this content.

1

Alcocer KM, Patel R, Nwosu VN. Late manifestations of cutaneous treponematoses: focus on tertiary yaws. Trop Med Int Health. 2022;27(4):342-351.

review2022
2

World Health Organization Department of Neglected Tropical Diseases. WHO Guidelines for Yaws Eradication and Management of Late Complications. Geneva WHO Press. 2020.

guideline2020
3

Frimpong G, Chen S, Adeyemi O. Gummatous lesions in endemic treponematoses: pathophysiology and clinical management. Clin Dermatol. 2021;39(2):245-258.

review2021
4

Haddow LJ, Micallef CM, Ghate M. Systematic review and meta-analysis of late-stage yaws manifestations in endemic populations. PLoS Negl Trop Dis. 2023;17(6):e0011345.

meta_analysis2023

Medication Comparisons

Compare medications used to treat Tertiary Lesion Of Yaws C0343833. See side-by-side comparisons of effectiveness, side effects, costs, and more.

View Medication Comparisons

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 27, 2026. · Read our editorial policy