Thyroid Cancer Nonmedullary 2 C4225426
A thyroid cancer arising from follicular cells, generally affecting adults. Treatment usually involves surgery to remove part or all of the thyroid, sometimes followed by radioactive iodine.
Key facts at a glance
- ICD-10
- C80.1
- ICD-11
- 2A00.0
- Body system
- oncologic
- Severity
- severe
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Warning signs - seek immediate care
Thyroid nodule
Neck swelling
Hoarseness
Dysphagia
Generalized symptoms
(oncologic)Significant symptoms that substantially affect daily functioning.
Frequency: Common at all stages
Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Combination drug regimen with regular assessment
Active treatment with regular monitoring by a healthcare provider is recommended.
Total thyroidectomy
Surgical removal of the entire thyroid gland is the standard primary treatment for nonmedullary thyroid cancer. This procedure eliminates the primary tumor and allows for accurate staging with lymph node assessment.
TSH suppression therapy
Levothyroxine therapy is initiated post-thyroidectomy to replace thyroid hormone and suppress thyroid-stimulating hormone, which may stimulate residual cancer cells.
Additional treatment options
Radioactive iodine ablation
Radioactive iodine treatment is used to ablate residual thyroid tissue and treat micrometastatic disease after thyroidectomy. This enhances the sensitivity of future thyroglobulin monitoring.
procedureThyroglobulin surveillance
Regular measurement of serum thyroglobulin levels and anti-thyroglobulin antibodies is performed to detect recurrent disease. Ultrasounds of the neck complement biochemical monitoring.
monitoringCalcium and vitamin D supplementation
Following thyroid surgery, calcium and vitamin D supplementation may be necessary due to potential hypoparathyroidism from parathyroid gland disturbance. Regular monitoring of calcium levels is recommended.
lifestyleWhen to seek medical help
Recognize when you need immediate medical attention.
See a doctor within 24 hours
Moderate to severe symptoms that may indicate worsening of this condition. Prompt medical evaluation is recommended.
Contact your healthcare provider or seek urgent care if symptoms worsen rapidly. Go to the emergency department for life-threatening symptoms.
Frequently asked questions
Common questions about this topic.
What is Thyroid Cancer Nonmedullary 2 C4225426?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
Haugen BR, Alexander EK, Bible KC, et al. 2015 American Thyroid Association Management Guidelines for Patients with Thyroid Nodules and Differentiated Thyroid Cancer. Thyroid. 2016.
Cabanillas ME, McFadden DG, Durante C. Thyroid cancer. Lancet. 2016.
Schlumberger M, Tahara M, Wirth LJ, et al. Lenvatinib versus placebo in radioiodine-refractory differentiated thyroid cancer. N Engl J Med. 2015.
Brose MS, Nutting CM, Jarzab B, et al. Sorafenib in radioactive iodine-refractory, locally advanced or metastatic differentiated thyroid cancer: a randomised, double-blind, phase 3 trial. Lancet. 2014.
Medication Comparisons
Compare medications used to treat Thyroid Cancer Nonmedullary 2 C4225426. See side-by-side comparisons of effectiveness, side effects, costs, and more.
View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy