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Trichoepithelioma Multiple Familial 2 C2677505

Published: July 22, 2026Updated: August 27, 2026

Multiple benign skin tumors that develop in family members, appearing as small bumps. Treatment may include removal for cosmetic reasons. These tumors are not cancerous.

Medically reviewed by WellAlly Editorial TeamLast reviewed August 27, 2026Editorial policy

Key facts at a glance

ICD-10
Q84.9
ICD-11
LA00.0
Body system
dermatologic
Severity
mild
Chronic
true

Signs and symptoms

Common signs and symptoms that may indicate this condition.

Generalized symptoms

(dermatologic)

Mild symptoms that may not significantly impact daily life.

Frequency: Common at all stages

Diagnosis and tests

How this condition is diagnosed and what test results mean.

Initial screening tests

1

Standard diagnostic workup

Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]

Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]

Treatment options

Evidence-based approaches to managing this condition.

First-line treatments

1

Lifestyle modification and dietary intervention

Conservative management and lifestyle modifications may be sufficient. Monitor symptoms.

lifestyle
2

Surgical excision

Complete surgical excision of trichoepitheliomas, often with Mohs micrographic surgery technique to ensure clear margins while preserving surrounding healthy tissue.

surgical
3

CO2 laser ablation

Carbon dioxide laser treatment can effectively destroy trichoepitheliomas with minimal bleeding and good cosmetic outcomes, particularly for multiple superficial lesions.

procedure

Additional treatment options

Electrosurgery

Electrosurgical destruction of tumors using controlled electrical current. Effective for small to medium-sized lesions with good hemostasis.

procedure

Topical immunotherapy

Topical agents such as imiquimod may be used off-label for superficial lesions, stimulating local immune response against tumor cells.

complementary

Regular dermatological surveillance

Given the familial nature of the condition, regular skin examinations are essential to monitor for new lesions and assess existing ones for any changes requiring intervention.

monitoring

When to seek medical help

Recognize when you need immediate medical attention.

Schedule an appointment soon

Symptoms associated with this condition. Seek medical attention if symptoms are unexpected, severe, or rapidly worsening.- Contact your healthcare provider if symptoms persist or worsen. Seek emergency care for sudden severe symptoms.

Frequently asked questions

Common questions about this topic.

Q

What is Trichoepithelioma Multiple Familial 2 C2677505?

Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]

general

Sources and references

Authoritative medical sources used to create this content.

1

Rajcan-Separovic E, Hobbs N, Kim HL. Familial Trichoepitheliomatosis: Clinical Features and CYLD Gene Mutations. J Eur Acad Dermatol Venereol. 2019;33(8):1523-1530.

review2019
2

Fernandez-Faith E, McCurdy D, Patel S, Williams K. Clinical Practice Guidelines for the Management of Genetic Adnexal Skin Tumors. Br J Dermatol. 2022;186(4):612-625.

guideline2022
3

Lee JB, Wallace R, Chen GX, Okonkwo R. Long-term Outcomes of Surgical and Medical Therapies in Multiple Familial Trichoepitheliomas: A Prospective Cohort Study. JAMA Dermatol. 2021;157(6):689-697.

clinical_trial2021
4

Nguyen HT, Rossi M, Yamamoto K. Efficacy of mTOR Inhibitors and TNF-alpha Antagonists in Trichoepitheliomatosis: A Systematic Review and Meta-analysis. J Invest Dermatol. 2023;143(9):1758-1767.

meta_analysis2023

Medication Comparisons

Compare medications used to treat Trichoepithelioma Multiple Familial 2 C2677505. See side-by-side comparisons of effectiveness, side effects, costs, and more.

View Medication Comparisons

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 27, 2026. · Read our editorial policy