Tuberous Sclerosis 3 Cn229773
A genetic disorder in the tuberous sclerosis family affecting multiple organ systems. Tumors may develop in various tissues. Individualized care addresses specific concerns.
Key facts at a glance
- ICD-10
- G40.909
- ICD-11
- 8A00.0
- Body system
- neurologic
- Severity
- moderate
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Warning signs - seek immediate care
Subependymal giant cell astrocytoma
Generalized symptoms
(neurologic)Noticeable symptoms that may vary in intensity over time.
Frequency: Common at all stages
Seizures
(neurologic)Developmental delay
(neurologic)Cortical tubers
(neurologic)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Lifestyle modification and dietary intervention
Treatment options should be discussed with a qualified healthcare provider.
mTOR Inhibitor Therapy
Systemic mTOR inhibitor therapy such as sirolimus or everolimus targets the underlying genetic pathway causing tumor growth in tuberous sclerosis, reducing tumor size in multiple organs including brain, kidneys, and skin.
Antiepileptic Medication
Anticonvulsant medications are prescribed to manage seizure activity, which is common in tuberous sclerosis complex patients due to cortical tubers affecting brain function.
Additional treatment options
Regular MRI Surveillance
Periodic magnetic resonance imaging of the brain and abdomen to monitor tumor progression, particularly subependymal giant cell astrocytomas and renal angiomyolipomas.
monitoringNeurosurgical Intervention
Surgical removal or laser ablation of problematic brain tumors causing seizures, hydrocephalus, or neurological symptoms when medical management fails or tumors become life-threatening.
surgicalNeurodevelopmental Support
Comprehensive neuropsychological evaluation and behavioral interventions to address learning disabilities, attention deficits, and autism spectrum characteristics commonly associated with tuberous sclerosis.
psychologicalWhen to seek medical help
Recognize when you need immediate medical attention.
Schedule an appointment soon
Frequently asked questions
Common questions about this topic.
What is Tuberous Sclerosis 3 Cn229773?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
Northrup H, Kohe K, Ewalt M, Bhatt J. Updated diagnostic criteria and surveillance recommendations for tuberous sclerosis complex. Neurology Clinical Practice. 2021.
Sands T, Jozwiak S, Trelinska J, Whiteman D. Mammalian target of rapamycin inhibitors in tuberous sclerosis complex: a comprehensive review. Expert Opinion on Pharmacotherapy. 2020.
Curatolo P, Moavero R, Pucatti G, De Vries P. Everolimus for subependymal giant cell astrocytoma in tuberous sclerosis complex: long-term follow-up from the EXIST-3 trial. Pediatric Neurology. 2022.
Henske E, Jozwiak S, Kingswood J, Sampson J. Epidemiology of tuberous sclerosis complex: global prevalence and diagnostic considerations. Orphanet Journal of Rare Diseases. 2023.
Medication Comparisons
Compare medications used to treat Tuberous Sclerosis 3 Cn229773. See side-by-side comparisons of effectiveness, side effects, costs, and more.
View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy