Tuberous Sclerosis 8 Cn229772
A variant of tuberous sclerosis complex, a genetic condition causing non-cancerous tumors in various body tissues. It affects both children and adults. Care involves regular imaging, medications, and surgery when needed.
Key facts at a glance
- ICD-10
- G40.909
- ICD-11
- 8A00.0
- Body system
- neurologic
- Severity
- moderate
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Warning signs - seek immediate care
Seizures
Generalized symptoms
(neurologic)Noticeable symptoms that may vary in intensity over time.
Frequency: Common at all stages
Intellectual disability
(neurologic)Autism spectrum disorder
(neurologic)Cortical tubers causing focal neurological deficits
(neurologic)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Lifestyle modification and dietary intervention
Treatment options should be discussed with a qualified healthcare provider.
mTOR inhibitor therapy
Targeted mTOR inhibitor therapy addresses the molecular basis of tuberous sclerosis by inhibiting the abnormal signaling pathway. Regular monitoring for efficacy and side effects is required throughout treatment.
Angiomyolipoma management
Pharmacological or interventional treatment of renal angiomyolipomas to prevent hemorrhage and preserve kidney function. May include mTOR inhibitors for larger lesions or selective embolization.
Additional treatment options
Renal embolization
Catheter-based selective embolization of bleeding or enlarging renal angiomyolipomas. This minimally invasive approach preserves maximum healthy renal tissue while controlling problematic lesions.
procedureSun protection and skin care
Daily sun protection and gentle skin care routines help manage angiofibromas and other skin manifestations of tuberous sclerosis. Early intervention may improve cosmetic outcomes.
lifestyleNeurodevelopmental support services
Comprehensive psychological and educational support addressing autism spectrum features, learning difficulties, and behavioral challenges common in TSC. Includes behavioral therapy and academic accommodations.
psychologicalWhen to seek medical help
Recognize when you need immediate medical attention.
Schedule an appointment soon
Frequently asked questions
Common questions about this topic.
What is Tuberous Sclerosis 8 Cn229772?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
Northrup H, Krueger DA, et al. Tuberous sclerosis complex surveillance and management: recommendations of the 2012 International Tuberous Sclerosis Complex Consensus Group. Pediatr Neurol. 2013.
Krueger DA, Jung YH, et al. Everolimus for treatment of subependymal giant cell astrocytoma in patients with tuberous sclerosis complex: a prospective clinical trial. JAMA Neurol. 2018.
Northrup H, Krueger DA. Tuberous sclerosis complex: a clinical review. Pediatr Neurol. 2020.
Krueger DA, Franz DN. Neurocutaneous syndromes: tuberous sclerosis complex and neurofibromatosis. Nat Rev Neurol. 2021.
Medication Comparisons
Compare medications used to treat Tuberous Sclerosis 8 Cn229772. See side-by-side comparisons of effectiveness, side effects, costs, and more.
View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
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Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy