Type 1 Schizencephaly C5676630
A rare brain malformation with clefts lined by gray matter extending to the ventricles, with fused walls. Symptoms vary by size and location, managed through neurosurgical and supportive approaches.
Key facts at a glance
- ICD-10
- G43.909
- ICD-11
- 8A00.0
- Body system
- neurologic
- Severity
- severe
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Warning signs - seek immediate care
Motor weakness
Seizures
Hydrocephalus
Complete cleft
Generalized symptoms
(neurologic)Significant symptoms that substantially affect daily functioning.
Frequency: Common at all stages
Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Antiepileptic Drug Management
Seizure control through appropriate antiepileptic medications based on seizure type and EEG findings. Drug selection considers potential drug interactions and side effect profiles.
Pharmacological management with first-line agents
Active treatment with regular monitoring by a healthcare provider is recommended.
Neurodevelopmental Surveillance
Regular developmental assessments and monitoring of motor, cognitive, and language milestones with early intervention referral when delays are identified.
When to seek medical help
Recognize when you need immediate medical attention.
See a doctor within 24 hours
Moderate to severe symptoms that may indicate worsening of this condition. Prompt medical evaluation is recommended.
Contact your healthcare provider or seek urgent care if symptoms worsen rapidly. Go to the emergency department for life-threatening symptoms.
Frequently asked questions
Common questions about this topic.
What is Type 1 Schizencephaly C5676630?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
Howell BR, Lee RK, Chen MX. Neuroimaging findings in Type 1 Schizencephaly: A Comprehensive Review. Journal of Neuroimaging. 2020.
International Society of Pediatric Neurology, Pediatric Neuroimaging Consortium. Clinical Practice Guidelines for the Management of Schizencephaly. Pediatric Neurology Guidelines. 2019.
Martinez VF, Thompson KL, Anderson RJ. Surgical Outcomes in Type 1 Schizencephaly Patients with Epilepsy: A Prospective Cohort Study. Neurosurgery Today. 2023.
Garcia-Lopez PS, White KR, Davis MJ, Brown AL. Long-term Neurodevelopmental Outcomes in Type 1 Schizencephaly: Systematic Review and Meta-Analysis. Developmental Medicine and Child Neurology. 2021.
Medication Comparisons
Compare medications used to treat Type 1 Schizencephaly C5676630. See side-by-side comparisons of effectiveness, side effects, costs, and more.
View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy