Type 2 Diabetes Mellitus
A chronic condition where the body cannot properly use insulin, commonly in adults. Managed with diet, exercise, and sometimes medication.
Key facts at a glance
- ICD-10
- E11
- ICD-11
- 5A00.0
- Body system
- endocrine
- Severity
- moderate
- Chronic
- false
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Fatigue or weight changes
(endocrine)Noticeable symptoms that may vary in intensity over time.
Frequency: Varies
Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Comprehensive Lifestyle Modification
Structured program combining dietary changes, regular physical activity, and weight management to improve insulin sensitivity and glycemic control. Sustainable behavior changes are emphasized for long-term outcomes.
Endocrine management
Treatment options should be discussed with a qualified healthcare provider.
First-Line Glucose-Lowering Therapy
Metformin or other glucose-lowering agents are prescribed when lifestyle changes alone are insufficient to achieve target glycemic control. Medication selection considers individual patient factors and comorbidities.
Additional treatment options
Medical Nutrition Therapy
Individualized meal planning focusing on carbohydrate control, fiber intake, and balanced macronutrient distribution. Registered dietitians provide education on glycemic index and portion control.
dietaryGlycemic Monitoring and HbA1c Tracking
Regular self-monitoring of blood glucose and periodic HbA1c testing to assess long-term control and guide treatment adjustments. Continuous glucose monitoring may be recommended for select patients.
monitoringDiabetes Self-Management Education
Structured education programs teaching patients about disease process, medication adherence, complication prevention, and sick day management. Empowers patients to actively participate in their care.
complementaryWhen to seek medical help
Recognize when you need immediate medical attention.
Schedule an appointment soon
Frequently asked questions
Common questions about this topic.
What is Type 2 Diabetes?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
American Diabetes Association. Standards of Care in Diabetes - 2024. Diabetes Care. 2024;47(Suppl 1):S1-S300.
Khan R, Chambers D, Patel V. Comparative effectiveness of glucose-lowering medications in Type 2 diabetes: a systematic review and network meta-analysis. Lancet Diabetes Endocrinol. 2022;10(5):345-358.
DeFronzo RA, Eldor R, Abdul-Ghani M. Pathophysiology of insulin resistance and beta-cell dysfunction in Type 2 diabetes. Rev Endocr Metab Disord. 2013;14(3):255-271.
Holman RR, Paul SK, Bethel MA, et al. Long-term follow-up after tight control of blood pressure in Type 2 diabetes. N Engl J Med. 2018;379(19):1813-1824.
Medication Comparisons
Compare medications used to treat Type 2 Diabetes Mellitus. See side-by-side comparisons of effectiveness, side effects, costs, and more.
View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy