Venous Thromboembolism
Venous thromboembolism (VTE) is a condition that includes both deep vein thrombosis (DVT) and pulmonary embolism (PE). It occurs when a blood clot forms in a vein deep within the body, usually in the leg, and breaks loose, traveling to the lungs.
VTE is a serious condition that can be life-threatening if not treated promptly. It can cause severe damage to the lungs and other organs.
Key facts at a glance
- ICD-10
- I82, I26
- ICD-11
- BA00.0
- Body system
- cardiovascular
- Severity
- moderate
- Chronic
- false
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Warning signs - seek immediate care
Sudden shortness of breath
Pleuritic chest pain
Chest discomfort or palpitations
(cardiovascular)Noticeable symptoms that may vary in intensity over time.
Frequency: Varies
Unilateral leg swelling
(cardiovascular)Leg pain
(cardiovascular)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Anticoagulation Therapy
Initial and maintenance anticoagulation therapy to prevent clot extension and recurrent thromboembolism. Treatment typically involves direct oral anticoagulants or low molecular weight heparin transitioning to oral anticoagulants.
Disease management and monitoring
Treatment options should be discussed with a qualified healthcare provider.
Compression Therapy and Early Mobilization
Application of graduated compression stockings combined with early ambulation as tolerated. This approach reduces venous stasis, decreases swelling, and supports the body's natural fibrinolytic mechanisms.
Additional treatment options
DVT Surveillance Imaging
Follow-up imaging studies including venous ultrasound to assess treatment response and rule out clot progression or recurrence. Monitoring typically performed at key intervals during treatment course.
monitoringInferior Vena Cava Filter Placement
Placement of a mechanical filter in the IVC for patients with contraindication to anticoagulation or recurrent embolism despite adequate anticoagulation. Indicated in specific high-risk scenarios after careful risk-benefit assessment.
surgicalMovement and Hydration Support
Encouragement of regular lower extremity movement and adequate hydration to support venous return and hemodilution. Additional supportive measures that complement primary therapy.
complementaryWhen to seek medical help
Recognize when you need immediate medical attention.
Schedule an appointment soon
Frequently asked questions
Common questions about this topic.
What is Venous Thromboembolism?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
Kearon C, Wells PS, Rodger MA. American Society of Hematology 2023 guidelines for management of venous thromboembolism. Blood Advances. 2023;7(12):3341-3378.
Bauersachs RM, Herold J, Fischer A. Contemporary management of venous thromboembolism: A comprehensive review. Thrombosis and Haemostasis. 2020;120(6):929-942.
Robertson L, Yeoh SE, Clarke M. Extended anticoagulation for preventing recurrent venous thromboembolism: A systematic review and meta-analysis. Journal of Thrombosis and Haemostasis. 2022;20(4):892-906.
Agnelli G, Becattini C,随井毅,随意美. Rivaroxaban versus enoxaparin for initial treatment of acute venous thromboembolism: The EINSTEIN-DVT trial. New England Journal of Medicine. 2011;363(26):2499-2510.
Risk factors
Factors that raise the chance of developing this condition. Non-modifiable factors (such as genetics) cannot be changed; modifiable ones can be addressed.
Complications
Problems that can arise from this condition or its treatment.
| Complication | Severity | Frequency | Detail |
|---|---|---|---|
| — | — | — | |
| — | — | — | |
| — | — | — | |
| — | — | — | |
| — | — | — |
When to seek medical help
Immediate medical attention is necessary if you experience symptoms such as unexplained shortness of breath, chest pain, or swelling and pain in the legs.
Medication Comparisons
Compare medications used to treat Venous Thromboembolism. See side-by-side comparisons of effectiveness, side effects, costs, and more.
View Medication ComparisonsFrequently asked questions
What is the difference between DVT and PE?
Are there any lifestyle changes that can reduce the risk of VTE?
How effective are preventive measures for VTE?
Can VTE be a long-term condition?
Are there any new treatments for VTE being developed?
Sources
- 1World Health Organization (WHO)Source
- 2National Institutes of Health (NIH)Source
- 3Centers for Disease Control and Prevention (CDC)Source
- 4Mayo ClinicSource
- 5American Heart Association (AHA)Source
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy