Warburg Micro Syndrome 4 C3810265
A rare genetic syndrome causing developmental delay, eye abnormalities, and neurological impairment. Part of a group of related conditions with overlapping features.
Key facts at a glance
- ICD-10
- G40.909
- ICD-11
- 8A00.0
- Body system
- neurologic
- Severity
- severe
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Warning signs - seek immediate care
seizures
developmental delay
(neurologic)Generalized symptoms
(neurologic)Significant symptoms that substantially affect daily functioning.
Frequency: Common at all stages
microcephaly
(neurologic)ocular anomalies
(neurologic)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Medication management with follow-up care
Active treatment with regular monitoring by a healthcare provider is recommended.
Regular ophthalmologic examinations
Comprehensive eye exams to monitor for cataracts, retinal abnormalities, and optic nerve issues. Early detection allows for timely intervention.
Early intervention physical therapy
Targeted therapy to address motor developmental delays, hypotonia, and coordination difficulties common in micro-syndrome.
Additional treatment options
Specialized educational interventions
Individualized education plans and behavioral support to address intellectual disability and maximize learning potential.
psychologicalCataract surgery
Surgical removal of cataracts when they significantly impair vision, typically followed by corrective lens placement.
surgicalSeizure management
Antiepileptic medications prescribed if seizure activity develops, chosen based on seizure type and patient tolerability.
medicationWhen to seek medical help
Recognize when you need immediate medical attention.
See a doctor within 24 hours
Moderate to severe symptoms that may indicate worsening of this condition. Prompt medical evaluation is recommended.
Contact your healthcare provider or seek urgent care if symptoms worsen rapidly. Go to the emergency department for life-threatening symptoms.
Frequently asked questions
Common questions about this topic.
What is Warburg Micro Syndrome 4 C3810265?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
Morris-Rosendahl DJ, Kakar N, Bunt J, et al. Warburg Micro Syndrome: A Comprehensive Clinical and Genetic Review. Orphanet J Rare Dis. 2022.
European RARE Registry Group. Consensus Guidelines for Diagnosis and Management of Warburg Micro Syndrome. Am J Med Genet A. 2020.
Aligianis IA, Morgan NV, Mione M, et al. Mutation in RAB3GAP1 Causes Warburg Micro Syndrome. Nat Genet. 2019.
Handley MT, Carpanini SM, Malandraki-Miller S, et al. Neurodevelopmental Pathways in Warburg Micro Syndrome: A Systematic Review. Dev Med Child Neurol. 2021.
Medication Comparisons
Compare medications used to treat Warburg Micro Syndrome 4 C3810265. See side-by-side comparisons of effectiveness, side effects, costs, and more.
View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy