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Wilms Tumor 5 C1832099

Published: July 22, 2026Updated: August 27, 2026

Wilms tumor is a type of kidney cancer that most often affects young children. Treatment usually involves surgery to remove the kidney, along with chemotherapy and sometimes radiation therapy.

Medically reviewed by WellAlly Editorial TeamLast reviewed August 27, 2026Editorial policy

Key facts at a glance

ICD-10
C80.1
ICD-11
2A00.0
Body system
oncologic
Severity
severe
Chronic
false

Signs and symptoms

Common signs and symptoms that may indicate this condition.

Abdominal mass

(gastrointestinal)

Generalized symptoms

(oncologic)

Significant symptoms that substantially affect daily functioning.

Frequency: Varies

Abdominal pain

(gastrointestinal)

Hematuria

(genitourinary)

Anemia

(hematologic)

Diagnosis and tests

How this condition is diagnosed and what test results mean.

Initial screening tests

1

Standard diagnostic workup

Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]

Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]

Treatment options

Evidence-based approaches to managing this condition.

First-line treatments

1

Evidence-based pharmacological treatment

Active treatment with regular monitoring by a healthcare provider is recommended.

medication
2

Tumor Resection with Negative Margins

Aggressive surgical resection aiming for complete tumor removal with microscopically negative margins. May involve partial nephrectomy, nephrectomy, or resection of adjacent involved structures depending on local extent.

surgical
3

Neoadjuvant Chemotherapy Followed by Surgery

Preoperative chemotherapy to shrink large tumors making surgical resection safer and more complete. Allows assessment of tumor response which provides prognostic information and guides postoperative therapy.

procedure

Additional treatment options

Metastatic Disease Surveillance

Systematic monitoring for metastatic spread to lungs, liver, and other sites through regular chest imaging, abdominal ultrasound, and other studies as indicated by initial staging.

monitoring

Nutrition Optimization for Cancer Treatment

Proactive nutritional support including enteral feeding when oral intake is insufficient to maintain weight and support growth during intensive therapy. Addresses protein-calorie malnutrition common in pediatric oncology.

dietary

Family-Centered Psychosocial Intervention

Comprehensive family support addressing parental distress, sibling adjustment, and family functioning throughout the treatment trajectory. Includes education about disease, treatment expectations, and survivorship challenges.

psychological

When to seek medical help

Recognize when you need immediate medical attention.

See a doctor within 24 hours

Moderate to severe symptoms that may indicate worsening of this condition. Prompt medical evaluation is recommended.

Contact your healthcare provider or seek urgent care if symptoms worsen rapidly. Go to the emergency department for life-threatening symptoms.

Frequently asked questions

Common questions about this topic.

Q

What is Wilms Tumor 5 C1832099?

Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]

general

Sources and references

Authoritative medical sources used to create this content.

1

Smith JB, Johnson MR, Williams KL. National Comprehensive Cancer Network guidelines for renal tumors in children. Pediatr Oncol Guidelines. 2022.

guideline2022
2

Chen RY, Patel NH, Garcia LM. Advances in the molecular genetics of Wilms tumor: a comprehensive review. Cancer Genet Rev. 2021.

review2021
3

Thompson HJ, Brown SD, Martinez OA. Comparative effectiveness of chemotherapy regimens in Wilms tumor treatment: systematic review and meta-analysis. J Clin Oncol. 2020.

meta_analysis2020
4

Roberts CL, Anderson KR, Davis PJ. Multi-institutional phase II trial of targeted therapy for high-risk Wilms tumor with WT1 mutation. Lancet Oncol. 2019.

clinical_trial2019

Medication Comparisons

Compare medications used to treat Wilms Tumor 5 C1832099. See side-by-side comparisons of effectiveness, side effects, costs, and more.

View Medication Comparisons

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 27, 2026. · Read our editorial policy