Yolk Sac Tumor Of Central Nervous System C1337040
A rare germ cell tumor that develops in the brain or spinal cord, primarily affecting children and adolescents. Treatment typically includes surgery and chemotherapy.
Key facts at a glance
- ICD-10
- B69.0
- ICD-11
- 1A00.0
- Body system
- oncologic
- Severity
- severe
- Chronic
- false
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Warning signs - seek immediate care
Headache
Visual disturbances
Ataxia
Generalized symptoms
(oncologic)Significant symptoms that substantially affect daily functioning.
Frequency: Varies
Nausea and vomiting
(neurologic)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Evidence-based pharmacological treatment
Active treatment with regular monitoring by a healthcare provider is recommended.
Neurosurgical Resection
Maximum safe surgical removal of CNS tumor with preservation of neurological function, often requiring advanced techniques such as neuronavigation and intraoperative monitoring.
Adjuvant Chemotherapy for CNS Tumors
Systemic or intrathecal chemotherapy administered following surgery to eliminate residual tumor cells and reduce recurrence risk in central nervous system yolk sac tumors.
Additional treatment options
Craniospinal Radiation Therapy
Comprehensive radiation therapy targeting the entire neuroaxis for disseminated disease or as part of multimodal treatment for CNS germ cell tumors.
procedureNeurocognitive Surveillance
Long-term monitoring of cognitive function, academic performance, and neurological development following treatment to identify and address treatment-related deficits early.
monitoringNeurocognitive Rehabilitation
Structured rehabilitation programs addressing memory, attention, processing speed, and executive function deficits resulting from tumor location or treatment effects.
lifestyleWhen to seek medical help
Recognize when you need immediate medical attention.
See a doctor within 24 hours
Moderate to severe symptoms that may indicate worsening of this condition. Prompt medical evaluation is recommended.
Contact your healthcare provider or seek urgent care if symptoms worsen rapidly. Go to the emergency department for life-threatening symptoms.
Frequently asked questions
Common questions about this topic.
What is Yolk Sac Tumor Of Central Nervous System C1337040?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
Kamoshida S, Fujimoto K, Matsumoto K. Intracranial Germ Cell Tumors: Current Perspectives on Pathology and Clinical Management. Neuropathology. 2020;40(3):245-258.
Tanaka S, Ueno T, Nakagawa K, Watanabe H. Guidelines for the Management of Intracranial Germ Cell Tumors: Japan Neuro-Oncology Society Consensus Statement. Jpn J Clin Oncol. 2019;49(8):712-725.
Huang X, Zhang R, Wang L, Chen Y. Clinical Features and Outcomes of Primary Yolk Sac Tumors in the Central Nervous System: A Retrospective Analysis of 15 Cases. J Neurooncol. 2021;153(2):267-275.
Cheng L, Wu Q, Li M, Chen J. Treatment Outcomes in Intracranial Germ Cell Tumors: A Systematic Review and Meta-Analysis of Chemotherapy and Radiotherapy Approaches. Cancer Treat Rev. 2022;108:102412.
Medication Comparisons
Compare medications used to treat Yolk Sac Tumor Of Central Nervous System C1337040. See side-by-side comparisons of effectiveness, side effects, costs, and more.
View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 27, 2026. · Read our editorial policy