Lecanemab in early Alzheimer's disease
van Dyck CH, Swanson CJ, Ayes P
New England Journal of Medicine · 2023
This randomized controlled trial evaluates the intervention under study in relation to the primary clinical outcome. Includes 1,795 participants. Evidence level: Ib.
循证研究：Lecanemab治疗早期阿尔茨海默病
Key facts at a glance
- DOI
- 10.1056/NEJMoa2212948
- PMID
- 36449413
- Journal
- New England Journal of Medicine
- Year
- 2023
- Study type
- rct
- Evidence level
- Ib
- Sample size
- 1795
- Intervention
- Lecanemab 10mg/kg vs 安慰剂
- Primary outcome
- CDR-SB 变化
- Open access
- false
Study Overview
This randomized controlled trial enrolled 1,795 participants and examined the primary clinical outcome.
Key Findings
Results regarding the primary clinical outcome are presented.
Clinical Conclusions
See original publication for detailed findings. Evidence level: Ib.
Abstract
"This randomized controlled trial enrolled 1,795 participants, investigating the effects of Lecanemab 10mg/kg vs 安慰剂 on CDR-SB 变化.
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Medically reviewed by WellAlly Editorial Team Last reviewed October 18, 2026. · Read our editorial policy